Adherence to intermittent preventive treatment for malaria with sulphadoxine-pyrimethamine and outcome of pregnancy among parturients in South East Nigeria

Figures & data

Table 1 Sociodemographic characteristics of participants according to uptake of IPTp-SP

Sociodemographic variable	Number of participants n=516 (%)	Participants who had no IPTp-SP n=149 (%)	Participants who had ≥ one dose of IPTp-SP n=367 (%)	P-value
Age (years)
<20	25 (4.9)	15 (10.1)	10 (2.7)
20–29	310 (60.0)	66 (44.3)	244 (66.5)	0.02
30–39	178 (34.5)	65 (43.6)	113 (30.8)
≥40	3 (0.6)	3 (2.0)	0 (0)
Parity
≤1	233 (45.2)	33 (22.1)	200 (54.5)
2–4	267 (51.7)	102 (68.5)	165 (44.9)	<0.0001
≥5	16 (3.1)	14 (9.4)	2 (0.5)
Educational status
Primary or less	121 (23.2)	66 (44.3)	57 (14.9)	<0.0001
Secondary or higher	395 (76.6)	83 (55.7)	312 (85.1)
Marital status
Married	501 (97.1)	136 (91.3)	365 (99.5)	0.02
Single	15 (2.9)	13 (8.7)	2 (0.5)
Residence
Urban	186 (36.0)	69 (46.3)	117 (31.9)	0.04
Rural	330 (64.0)	80 (54.7)	250 (68.1)

Abbreviation: IPTp-SP, intermittent preventive treatment for malaria with sulphadoxine-pyrimethamine.

Table 2 Use of IPTp, doses received, and reasons for nonadherence

	Number of women (%)
Received IPTp
Yes	367 (71.2)
No	149 (28.8)
Number of doses of IPTp received (n=367)
One	130 (35.4)
Two	219 (59.7)
Three	18 (4.9)
Reasons for not receiving IPTp
No IPTp at all (n=149)
Did not see the need	49 (32.9)
Preferred herbs	82 (55.0)
Religious reasons	18 (12.1)
Failed to take subsequent doses (n=130)
Not prescribed	40 (31.0)
Individual reasons	89 (68.8)
Did not have money when it was prescribed	41 (31.5)
Did not know it was that important after taking the first dose	22 (16.9)
Simply forgot	16 (12.3)
First dose caused weakness and feeling of ill health	10 (7.7)
Allergy	1 (0.2)

Abbreviation: IPTp, intermittent preventive treatment.

Table 3 Comparison of maternal and neonatal malaria with use and nonuse of IPTp

	IPTp (n=367)	No IPTp (n=149)	RR (95% CI)	P-value
	n (%)	n (%)
Maternal (n=516)
Malaria	74 (20.2)	127 (85)	2.53 (2.10–3.04)	<0.001*
No malaria	293 (79.8)	22 (15)
Neonate (n=516)
Malaria	12 (3.4)	11 (7.4)	1.38 (0.93–2.05)	0.003*
No malaria	355 (96.6)	138 (92.6)

Note:

* Represents statistically significant.

Abbreviations: CI, confidence interval; IPTp, intermittent preventive treatment; RR, risk ratio.