Clinical utility and patient considerations in the use of the sitagliptin–metformin combination in Chinese patients

Figures & data

Table 1 Characteristics of the included trials

Study		HbA1c (%)	Fasting plasma glucose (mmol/L)	Postprandial glucose (mmol/L)	Insulin (mU/L)	BMI (kg/m^2)	Cholesterol (mmol/L)	Triglycerides (mmol/L)	Weight (kg)
Wu et al^Citation30	Baseline	7.82±0.84	9.52±2.23	13.25±4.43	10.2±2.1	24.82±2.26	4.71±2.02	2.95±1.52
	Week 12	7.11±0.92	8.23±2.42	10.35±3.71	13.2±3.4	24.65±2.48	4.22±1.87	2.28±1.09
Fan^Citation31	Baseline	9.2±2.4	9.4±2.4	13.6±4.5
	Week 12	6.2±2.1	6.4±1.8	8.1±2.7
Liang and Zou^Citation32	Baseline	8.5±0.8	9.1±0.9				5.1±1.3	1.6±0.5	70.2±8.8
	Week 12	7.8±1.0	8.0±0.8				4.6±0.7	1.3±0.3	69.3±8.7
Li et al^Citation33	Baseline	8.8±0.7	8.9±0.6	13.3±2.9
	Week 24	6.4±0.7	6.3±0.7	8.0±1.3
Sun et al^Citation34	Baseline	8.9±1.5	8.4±1.3	13.1±4.7	27.6±6.8	27.6±1.8			73.4±6.3
	Week 12	8.2±1.8	6.1±0.9	8.4±2.8	16.2±5.2	27.2±1.2			72.1±7.1
Jiao et al^Citation35	Baseline	8.0±1.5	9.0±1.6	14.2±2.3	10.2±2.1	24.9±2.1
	Week 12	6.1±1.2	5.6±1.5	8.2±1.3	13.2±3.1	20.7±1.5
Qu et al^Citation36	Baseline	9.1±2.2	9.3±2.2	13.3±4.4
	Week 12	6.4±2.0	6.3±1.7	8.2±2.7
Huang^Citation37	Baseline	8.7±1.1	9.8±1.4	14.5±1.6		25.7±1.5
	Week 12	6.5±1.0	5.6±1.6	8.7±1.6		20.2±2.51
Duan et al^Citation38	Baseline	10.3±1.2	11.9±1.33	17.01±1.91	12.95±0.90	28.9±1.4
	Month 6	8.1±1.2	8.17±1.22	10.16±1.68	9.22±1.93	27.4±1.2

Abbreviations: BMI, body mass index; HBA_1c, glycated hemoglobin.

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