Figures & data
Figure 1 Cited reasons for those who stopped taking ticagrelor.
Abbreviation: CABG, coronary artery bypass surgery.
Table 1 Characteristics of patients who continued or prematurely stopped ticagrelor
Figure 2 Univariate predictors of having an event in the registry.
Notes: Presenting with shock and premature stopping of ticagrelor were predictive of having an event in our registry. Age younger than 65 years and off-label use of ticagrelor were associated with decreased events. “Within region” means within 1 hour driving distance to the percutaneous coronary intervention facility. Off-label use for ticagrelor was defined as those who did not meet inclusion and/or who met exclusion criteria.
Abbreviations: STEMI, ST-segment elevation myocardial infarction; NSTEMI, non-ST-segment elevation myocardial infarction; CABG, coronary artery bypass surgery; OR, odds ratio; CI, confidence interval.
Abbreviations: STEMI, ST-segment elevation myocardial infarction; NSTEMI, non-ST-segment elevation myocardial infarction; CABG, coronary artery bypass surgery; OR, odds ratio; CI, confidence interval.
Figure 3 Multivariate predictors of having an event.
Notes: A test of the full model against a constant-only model was statistically significant, indicating that the predictors as a set reliably distinguished between those having an adverse event and those not having one [model χ2 (3) =39.84; P<0.001]. Nagelkerke’s R2 of 0.36 indicated a moderate relationship between prediction and grouping. Prediction success overall was 94%. The Wald criterion demonstrated that all three predictors contributed significantly to the model (age, P<0.005; shock, P<0.001; ticagrelor use, P<0.05).
Abbreviations: CI, confidence interval; OR, odds ratio.
Abbreviations: CI, confidence interval; OR, odds ratio.
Table 2 Events in Southern Saskatchewan Ticagrelor Registry
Table 3 Bleeding endpoints