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Original Research

Analysis of spontaneous inquiries about suspected adverse drug reactions posted by the general public on the electronic Japanese bulletin board “Yahoo! Japan Chiebukuro”

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Pages 511-521 | Published online: 08 Apr 2016

Figures & data

Table 1 Brand names of medicines used for extracting inquiries related to ADRs from the Japanese electronic bulletin board site, Yahoo! Japan Chiebukuro

Table 2 Medicines suspected of causing ADRs found in the inquiries along with those used for retrieval terms

Table 3 Symptoms or signs related to ADRs described in the inquiries

Figure 1 Comparison between the proportion of symptoms/signs related to ADRs for Predonine described in the inquiries posted to Yahoo! Japan Chiebukuro (when the inquiry had multiple items, all items were counted) and those in its interview form.

Notes: Filled bar: the rate of the number of each symptom/sign related to ADRs described in the inquiries posted to Yahoo! Japan Chiebukuro to that of all symptoms/signs (n=94). Unfilled bar: the rate of the number of each symptom/sign to that of all symptoms/signs (n=512) related to ADRs found in the interview form of Predonine® tablet 5 mg.
Abbreviation: ADR, adverse drug reaction.
Figure 1 Comparison between the proportion of symptoms/signs related to ADRs for Predonine described in the inquiries posted to Yahoo! Japan Chiebukuro (when the inquiry had multiple items, all items were counted) and those in its interview form.

Figure 2 Comparison between the proportion of symptoms/signs related to ADRs for Tamiflu described in the inquiries posted to Yahoo! Japan Chiebukuro (when the inquiry had multiple items, all items were counted) and those in its interview form.

Notes: Filled bar: the rate of the number of each symptom/sign related to ADRs described in the inquiries posted to Yahoo! Japan Chiebukuro to that of all symptoms/signs (n=81). Unfilled bar: the rate of the number of each symptom/sign to that of all symptoms/signs (n=243) related to ADRs found in the interview form of Tamiflu® capsule 75 mg.
Abbreviation: ADR, adverse drug reaction.
Figure 2 Comparison between the proportion of symptoms/signs related to ADRs for Tamiflu described in the inquiries posted to Yahoo! Japan Chiebukuro (when the inquiry had multiple items, all items were counted) and those in its interview form.

Figure 3 Comparison between the proportion of symptoms/signs related to ADRs for Paxil described in the inquiries posted to Yahoo! Japan Chiebukuro (when the inquiry had multiple items, all items were counted) and those in its interview form.

Notes: Filled bar: the rate of the number of each symptom/sign related to ADRs described in the inquiries posted to Yahoo! Japan Chiebukuro to that of all symptoms/signs (n=248). Unfilled bar: the rate of the number of each symptom/sign to that of all symptoms/signs (n=5,123) related to ADRs found in the interview form of Paxil® tablets 5 mg, 10 mg and 20 mg.
Abbreviation: ADR, adverse drug reaction.
Figure 3 Comparison between the proportion of symptoms/signs related to ADRs for Paxil described in the inquiries posted to Yahoo! Japan Chiebukuro (when the inquiry had multiple items, all items were counted) and those in its interview form.

Table 4 Completion rate for questionnaire items shared in the three national self-reporting ADR systems

Table 5 Timecourse from starting medication to developing ADRs as described in the inquiries

Table 6 Purpose of the ADR inquiries on Yahoo! Japan Chiebukuro