Comparison Of The Children Neuropsychological And Behavior Scale And The Griffiths Mental Development Scales When Assessing The Development Of Children With Autism

Figures & data

Table 1 Characteristics Of The Children With ASD Included In The Study (mean ± SD)

Item	ASD (n=139)
Age (mo)	49.9±12.3
Gender (boys:girls)	114:25 (4.6:1)
Total ABC score	53.6±18.5
Total CARS score	32.7±5.2
Communication Warning Behavior score of the CNBS-R2016 subscale	40.8±17.1

Table 2 Correlation Between The CNBS-R2016 And Its Corresponding GDS-C Scales

Variable (CNBS-R2016 Vs GDS-C)	r	p value
GQ	0.854**	<0.001
Gross Motor/Locomotor	0.873**	<0.001
Personal-Social	0.857**	<0.001
Language/Hearing-Speech	0.891**	<0.001
Fine Motor/Eye-Hand Coordination	0.808**	<0.001
Adaptive Behavior/Performance	0.766**	<0.001
Adaptive Behavior/Practical Reasoning	0.507**	<0.001

Note: **P < 0.001.

Abbreviations: CNBS-R2016, The newly revised Children Neuropsychological and Behavior Scale; GDS-C, Griffiths Mental Development Scales for China; GQ, general quotient.

Table 3 General And Subscale Quotients Of The GDS-C And CNBS-R2016 (mean±sd)

GDS-C		CNBS-R2016
GQ	62.4±19.9	GQ	66.8±17.9
Subscale A	76.2±19.3	Gross Motor	79.3±18.8
Subscale B	62.4±19.8	Personal-Social Behavior	65.4±22.4
Subscale C	54.7±26.2	Language	58.0±25.5
Subscale D	65.6±21.8	Fine Motor	65.4±19.2
Subscale E	69.1±24.5	Adaptive Behavior	65.8±20.6
Subscale F (n=77)	72.7±23.1	-	-

Abbreviations: GDS-C, Griffiths Mental Development Scales for China; CNBS-R2016, The newly revised Children Neuropsychological and Behavior Scale; GQ, general quotient.

Table 4 Number Of Children With A Developmental Delay According To The General And Subscale Quotients Of The CNBS-R2016 And GDS-C (n, %)

Variable	CNBS-R2016	GDS-C	χ^2	p value
GQ	77 (55.4%)*	94 (67.6%)	4.391	0.036
Gross Motor/Locomotor	41 (29.5%)	55 (39.6%)	3.119	0.077
Personal-Social	80 (57.6%)	92 (66.2%)	2.196	0.138
Language/Hearing-Speech	105 (75.5%)	97 (69.8%)	1.159	0.282
Fine Motor/Eye-Hand Coordination	78 (56.1%)	80 (57.6%)	0.059	0.809
Adaptive Behavior/Performance	78 (56.1%)	75 (54.0%)	0.131	0.718
Practical Reasoning	–	41/77 (53.2%)	–	–
Delayed in ≥2 domains	95 (68.3%)	94 (67.6%)	0.017	0.898

Note: *Significantly different from the percentage of a delay by the GDS-C (p<0.05).

Abbreviations: GDS-C, Griffiths Mental Development Scales for China; CNBS-R2016, The newly revised Children Neuropsychological and Behavior Scale; GQ, general quotient.

Figure 1 ROC curve for discriminating children with ASD and developmental delay according to the CNBS-R2016 general or subscale quotient from those without a developmental delay using the GDS-C general or subscale quotient cut-off of 70 (mean −2 SDs) as a standard. (A) ROC curve of the CNBS-R2016 general quotient using the GDS-C general quotient cut-off of 70 as a standard. (B) ROC curve of the CNBS-R2016 gross motor quotient using the GDS-C subscale A quotient cut-off of 70 as a standard. (C) ROC curve of the CNBS-R2016 Personal-Social quotient using the GDS-C subscale B quotient cut-off of 70 as a standard. (D) ROC curve of the CNBS-R2016 Language quotient using the GDS-C subscale C quotient cut-off of 70 as a standard. (E) ROC curve of the CNBS-R2016 Fine Motor quotient using the GDS-C subscale D quotient cut-off of 70 as a standard. (F) ROC curve of the CNBS-R2016 Adaptive Behavior quotient using the GDS-C subscale E quotient cut-off of 70 as a standard.

Figure 2 Bland-Altman plots generated to compare the average CNBS-R2016 and GDS-C quotients to their differences. The limits of agreement (95% CI, ie, mean ± 1.96 SDs) are shown by dotted lines. (A) Comparison of the CNBS-R2016 general quotient (GQ) and the GDS-C GQ. Mean difference: 3.9 (95% CI −13.5 to 21.3). (B) Comparison of the CNBS-R2016 Gross Motor quotient (GMQ) and the GDS-C subscale A quotient (AQ). Mean difference: 3.1 (95% CI −15.7 to 21.9). (C) Comparison of the CNBS-R2016 Personal-Social quotient (PSQ) and the GDS-C subscale B quotient (BQ). Mean difference: 3.1 (95% CI −19.6 to 25.7). (D) Comparison of the CNBS-R2016 Language quotient (LQ) and the GDS-C subscale C quotient (CQ). Mean difference: 3.3 (95% CI −20.4 to 26.9). (E) Comparison of the CNBS-R2016 Fine Motor quotient (FMQ) and the GDS-C subscale D quotient (DQ). Mean difference: −0.2 (95% CI −25.5 to 25.1). (F) Comparison of the CNBS-R2016 Adaptive Behavior quotient (ABQ) and the GDS-C subscale E quotient (EQ). Mean difference: −3.3 (95% CI −34.4 to 27.8).