A Review on the Mechanism Between Different Factors and the Occurrence of Autism and ADHD

Figures & data

Table 1 Comparison of Trends in Neurodevelopmental Disorders and Neurotoxins in the General Environment in the United States Between 1992 and 2003¹

US Totals
Year	Mercury	Lead	PCB	PVC	ADHD	Autism	Autism% Age 6–22
1992	55998	4.40%	427320			15292	0.0257%
1993	26916	4.40%	164470			18695	0.0311%
1994	20952	4.40%	94962			22329	0.0368%
1995	23912		34432	9.83		28720	0.0469%
1996	25042		97945			33999	0.0549%
1997	38507	7.61%	987640		5.5%	42126	0.0674%
1998	289518	6.50%	6127249		5.9%	53644	0.0850%
1999	126792	5.03%	14598073		5.6%	65607	0.1030%
2000	71884	3.96%	1722883	12.85	6.6%	78928	0.1197%
2001	95690	3.03%	4646321		6.4%	97994	0.1469%
2002	100041	2.56%	3155954		7.2%	118071	0.1752%
2003	68231	2.00%	43228331		6.4%	140254	0.2061%

Figure 1 Comprehensive diagram of prevalence of Autism & ADHD and the amount of different kinds of neurotoxins in the United States between 1990 and 2007. Reproduced from Smith EE, Charest JM, Bedrosian KR, DeVault VL Neurotoxic chemicals in the environment. 2008.¹

Table 2 Comparison of Monoamine Neurotransmitters NE and 5-Ht in Blood of ADHD and Autism Children with Normal Infants ( ± s)

Group	n	NE (θ g/mL)	5-HT (ng/mL)
ADHD group	35	687±124*	1.0±0.3*
Autism group	35	176±14*	16.3±8.6*
Control group	40	359±84	4.7±1.2

Note: Compared with the control group, *p<0.01.

Smith EE, Charest JM, Bedrosian KR, DeVault VL Neurotoxic chemicals in the environment. 2008.

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