A Behavioral and Event-Related Potentials Study of Food-Related Inhibitory Control in Probable Binge Eating Disorder

Figures & data

Table 1 Demographic Characteristics of the Groups in the Behavioral Study

Variables	pBED Group (n=60)	HCs (n=60)	χ²/t	p
Age, years (M±SD)	19.13±0.89	19.37±1.18	−1.223	0.224
Gender, Female n (%)	46 (76.7)	47 (78.3)	0.048	0.827
Years of education (M±SD)	13.08±0.28	13.18±0.47	−1.420	0.158
BMI, kg/m^2 (M±SD)	21.95±3.66	21.04±1.69	1.760	0.082
Ethnicity, Hans n (%)	45 (75.0)	46 (76.7)	0.045	0.831
Home locality, Urban n (%)	45 (75.0)	44 (73.3)	0.043	0.835
Smoking status, yes n (%)	2 (3.3)	0 (0.0)	2.034	0.154
Drinking status, yes n (%)	3 (5.0)	2 (3.3)	0.209	0.648
BES scores (M±SD)	21.50±3.28	5.57±2.21	31.191***	<0.001

Note: ***p<0.001.

Abbreviations: pBED, probable Binge Eating Disorder; HCs, Healthy Controls; BES, Binge Eating Scale.

Table 2 Inhibitory Control Performance of the Groups on the Cognitive Tasks (M±SD)

Variables	pBED Group (n=60)	HCs (n=60)	t	p
Stop-Signal Task
Correct accuracy in Go-trials (%)	95.22±4.26	94.63±6.73	0.577	0.565
Correct accuracy in Stop-trials (%)	52.89±4.71	53.09±4.67	−0.244	0.808
Response time in Go-trials (ms)	619.94±184.50	631.45±187.37	−0.399	0.735
Stop-Signal Reaction Time (ms)	269.83±44.60	247.89±29.81	3.168**	0.002
Go/No Go Task
Correct accuracy in frequent-go trials (%)	94.26±6.12	94.50±4.41	−0.256	0.799
Correct accuracy in rare-go trials (%)	85.11±12.28	84.78±9.81	0.161	0.873
Correct accuracy in no-go trials (%)	65.21±13.60	64.45±12.86	0.314	0.754
Response time in frequent-go trials (ms)	240.15±33.68	241.38±28.98	−0.214	0.831
Response time in rare-go trials (ms)	243.89±33.95	243.36±34.02	0.085	0.932
Food-related Go/No Go Task
Correct accuracy in frequent-go trials (%)	95.09±5.32	95.19±5.26	−0.103	0.918
Correct accuracy in rare-go trials (%)	84.56±11.23	85.56±11.49	−0.485	0.629
Correct accuracy in no-go trials (%)	58.88±15.43	65.80±14.22	−2.555*	0.012
Response time in frequent-go trials (ms)	244.43±37.45	239.17±32.11	0.825	0.411
Response time in rare-go trials (ms)	249.47±41.42	244.48±36.83	0.696	0.488

Notes: *p<0.05, **p<0.01.

Abbreviations: pBED, probable Binge Eating Disorder; HCs, Healthy Controls.

Table 3 Demographics and Task Scores of the Sample in the Event-Related Potentials (ERPs) Study

Variables	pBED Group (n=35)	HCs (n=35)	χ²/t	p
Age, years (M±SD)	19.31±0.90	19.57±1.04	−1.108	0.272
Gender, Female n (%)	26 (74.3)	25 (71.4)	0.072	0.788
Years of education (M±SD)	13.14±0.36	13.26±0.51	−1.095	0.278
BMI, kg/m^2 (M±SD)	21.66±3.54	20.53±1.37	1.763	0.085
Ethnicity, Hans n (%)	23 (65.7)	24 (68.6)	0.065	0.799
Home locality, Urban n (%)	25 (71.4)	23 (65.7)	0.265	0.607
Smoking status, yes n (%)	1 (2.9)	0 (0.0)	1.014	0.314
Drinking status, yes n (%)	2 (5.7)	1 (2.9)	0.348	0.555
BES scores (M±SD)	20.97±2.93	5.26±1.88	26.718***	<0.001
Food-related Go/No Go Task (M±SD)
Correct accuracy in frequent-go trials (%)	94.91±5.95	95.18±5.68	−0.197	0.844
Correct accuracy in rare-go trials (%)	85.27±10.70	85.13±11.81	0.052	0.959
Correct accuracy in no-go trials (%)	58.98±14.53	67.52±13.14	−2.581*	0.012
Response time in frequent-go trials (ms)	244.55±35.90	244.82±30.51	−0.033	0.974
Response time in rare-go trials (ms)	246.40±39.14	251.80±34.61	−0.612	0.542

Notes: *p<0.05, ***p<0.001.

Abbreviations: pBED, probable Binge Eating Disorder; HCs, Healthy Controls; BES, Binge Eating Scale.

Table 4 Comparisons of P300 Latency (Ms) on the Food-Related Go/No Go Task (M±SD)

Electrode Sites	pBED Group (n=34)	HCs (n=34)	t	p
Frequent-go trials
FC1	367.82±33.47	350.77±37.33	1.984	0.051
FC2	371.03±42.48	349.85±40.18	2.112*	0.038
F3	366.32±42.98	351.06±37.22	1.565	0.122
F4	371.06±35.60	352.68±41.77	1.930	0.058
CZ	369.27±42.75	346.38±47.37	2.091*	0.040
PZ	334.15±43.93	318.18±45.25	1.477	0.145
FZ	366.94±42.63	350.85±39.15	1.621	0.110
FCz	370.62±34.41	354.71±48.45	1.561	0.123
Rare-go trials
FC1	393.94±33.62	376.03±41.84	1.946	0.056
FC2	388.97±47.95	371.74±39.39	1.620	0.110
F3	387.91±43.39	376.47±44.40	1.075	0.286
F4	391.97±41.95	376.85±42.78	1.471	0.146
CZ	391.74±39.23	377.82±41.81	1.415	0.162
PZ	380.97±48.68	367.00±60.20	1.052	0.297
FZ	389.32±44.05	378.44±39.32	1.075	0.286
FCz	382.82±43.29	357.09±39.33	2.566*	0.013
No-go trials
FC1	379.06±39.19	350.79±45.49	2.745**	0.008
FC2	389.53±38.38	368.15±34.56	2.414*	0.019
F3	388.77±40.23	360.24±38.47	2.989**	0.004
F4	388.06±37.08	368.24±33.70	2.307*	0.024
CZ	385.53±41.09	370.09±46.27	1.455	0.150
PZ	386.77±40.96	376.71±44.21	0.973	0.334
FZ	390.94±33.21	366.21±34.53	3.011**	0.004
FCz	388.09±36.86	371.97±44.57	1.625	0.109

Notes: *p<0.05, **p<0.01.

Abbreviations: pBED, probable Binge Eating Disorder; HCs, Healthy Controls.

Data Sharing Statement

Data could be obtained by contacting the corresponding author.