Triglycerides and Total Cholesterol Concentrations in Association with Hyperuricemia in Chinese Adults in Qingdao, China

Figures & data

Figure 1 Flow chart of participant included and excluded in cross-sectional analysis.

Abbreviations: UA, uric acid; TG, triglycerides; TC, total cholesterol.

Table 1 Baseline Characteristics of the Participants

	Men	Women	P value
Number, (%)	3806 (39.3)	5874 (60.7)	<0.001
Age, (years)	51.9±11	51.0±10.3	<0.001
School years>9, n (%)	1289(34.1)	1593(27.2)	<0.001
Unmarried, n (%)	181(4.8)	356(6.1)	0.006
Rural living, n (%)	2557(67.2)	3509(59.7)	<0.001
Personal monthly income (CNY), n (%)			<0.001
≤599	1447(39.4)	2985(53.0)
600～1999	1677(45.6)	2399(42.6)
≥2000	552(15.0)	244(4.3)
HUA, n (%)	756(19.9)	683(11.6)	<0.001
Current Smoking, n (%)	1978(52.3)	156(2.7)	<0.001
Current Alcohol-drinking, n (%)	1623(42.9)	81(1.4)	<0.001
BMI (kg/m^2)	25.2±3.4	25.6±3.7	<0.001
TG (mmol/L)	1.5±1.3	1.4±1.0	<0.001
TC (mmol/L)	5.3±1.0	5.3±1.1	0.093
UA (μmol/L)	352.9±83.6	277.9±68.8	<0.001

Abbreviations: BMI, body mass index; HUA, hyperuricemia; TG, triglycerides; TC, total cholesterol; UA, uric acid.

Table 2 Odds Ratio (95% Confidence Interval) for HUA in Association to Triglycerides and Total Cholesterol Concentration by Univariate Logistic Regression

	Men		Women
	OR	P	OR	P
TG		<0.001		<0.001
Normal TG	1.00		1.00
Borderline high TG	2.06(1.64, 2.60)	<0.001	2.75(2.23, 3.39)	<0.001
Hypertriglyceridemia	3.95(3.23, 4.84)	<0.001	4.80(3.91, 5.89)	<0.001
TC		0.037		<0.001
Normal TC	1.00		1.00
Borderline high TC	1.05(0.88, 1.26)	0.567	1.76(1.45, 2.12)	<0.001
Hypercholesterolemia	1.33(1.07, 1.65)	0.011	2.75(2.24, 3.37)	<0.001
Age	0.99(0.98, 0.99)	<0.001	1.05(1.04, 1.05)	<0.001
School years>9	1.81(1.53, 2.13)	<0.001	0.88(0.73, 1.06)	0.178
Unmarried	0.93(0.64, 1.36)	0.715	1.53(1.14, 2.05)	0.005
Rural living	0.64(0.55, 0.76)	<0.001	0.71(0.60, 0.83)	<0.001
Personal monthly income		<0.001		0.049
≤599	1.00		1.00
600～1999	1.45(1.21, 1.75)	<0.001	1.23(1.04, 1.45)	0.016
≥2000	2.16(1.71, 2.73)	<0.001	1.21(0.81, 1.79)	0.348
Current Smoking	0.70(0.60, 0.82)	<0.001	1.05(0.65, 1.71)	0.839
Current Alcohol-drinking	1.31(1.12, 1.54)	0.001	1.60(0.89, 2.86)	0.115
BMI	1.16(1.13, 1.19)	<0.001	1.12(1.10, 1.15)	<0.001
HDL-C	0.72(0.60, 0.88)	0.001	0.53(0.42, 0.66)	<0.001

Note: Bold values represent the significance.

Abbreviations: BMI, body mass index; HDL-C, high-density lipoprotein-cholesterol; TG, triglycerides; TC, total cholesterol.

Table 3 OR (95% CI) for HUA in Association to TG and TC Concentration by Multivariable Logistic Regression

	Men		Women
	OR	P	OR	P
TG		<0.001		<0.001
Normal TG	1.00		1.00
Borderline high TG	1.75(1.36, 2.24)	<0.001	2.08(1.66, 2.61)	<0.001
Hypertriglyceridemia	3.13(2.50, 3.94)	<0.001	3.53(2.80, 4.44)	<0.001
TC		0.578		<0.001
Normal TC	1.00		1.00
Borderline high TC	0.99(0.81, 1.20)	0.888	1.57(1.28, 1.94)	<0.001
Hypercholesterolemia	1.12(0.88, 1.44)	0.365	2.31(1.83, 2.93)	<0.001

Notes: Men: adjusted for age, school years, marital status, geographic division, personal monthly income, smoking status, alcohol-drinking status, BMI, HDL-C. Women: adjusted for age, school years, marital status, geographic division, personal monthly income, BMI, HDL-C. Bold values represent the significance.

Abbreviations: BMI, body mass index; TG, triglycerides; TC, total cholesterol.

Table 4 OR (95% CI) for HUA in Association to TG and TC Concentration by Stratified Analysis of Age

	Men		Women
	OR	P	OR	P
TG
<55 years		<0.001		<0.001
Normal TG	1.00		1.00
Borderline high TG	1.66(1.21, 2.28)	0.002	2.35(1.68, 3.27)	<0.001
Hypertriglyceridemia	3.39(2.58, 4.46)	<0.001	3.77(2.67, 5.34)	<0.001
≥55 years		<0.001		<0.001
Normal TG	1.00		1.00
Borderline high TG	2.41(1.72, 3.36)	<0.001	1.84(1.35, 2.51)	<0.001
Hypertriglyceridemia	3.97(2.80, 5.63)	<0.001	3.22(2.37, 4.38)	<0.001
TC
<55 years		0.088		<0.001
Normal TC	1.00		1.00
Borderline high TC	1.11(0.87, 1.41)	0.408	1.74(1.31, 2.31)	<0.001
Hypercholesterolemia	1.42(1.04, 1.95)	0.027	2.93(2.08, 4.13)	<0.001
≥55 years		0.254		0.002
Normal TC	1.00		1.00
Borderline high TC	0.77(0.55, 1.08)	0.127	1.31(0.96, 1.77)	0.086
Hypercholesterolemia	0.77(0.51, 1.18)	0.230	1.81(1.30, 2.51)	<0.001

Notes: Men: adjusted for age, school years, marital status, geographic division, personal monthly income, smoking status, alcohol-drinking status, BMI, HDL-C. Women: adjusted for age, school years, marital status, geographic division, personal monthly income, BMI, HDL-C. Bold values represent the significance.

Abbreviations: BMI, body mass index; TG, triglycerides; TC, total cholesterol.