Predictors of Outcome in Juvenile Myoclonic Epilepsy

Figures & data

Table 1 Basic Information of the Patients in Two Groups

	Total	No Remission	Remission	P-value
Number of patients	63	23 (36.5%)	40 (63.5%)	–
Age (yr)	20.4 ± 6.925	19.55 ± 6.479	21.08 ± 7.5	0.246
Female	30 (47.6%)	11 (47.8%)	19 (47.5%)	0.98
Febrile seizures	9 (14.2%)	6 (21.6%)	3 (7.5%)	0.098
Family history of epilepsy	5 (7.9%)	2 (8.7%)	3 (7.5%)	1.000
Age at onset (yr)				0.017
<16 years	40 (63.4%)	19 (82.6%)	21 (52.5%)
≥16 years	23 (36.5%)	4 (17.4%)	19 (47.5%)

Table 2 Clinical and EEG Data of the Patients in Two Groups

Variables	Total	No Remission	Remission	P-value
Seizure types
MS only	10 (15.8%)	5 (21.7%)	5 (12.5%)	0.543
MS+GTCS	57 (90.4%)	20 (86%)	37 (92.5%)	0.783
MS+GTCS+AS	8 (12.6%)	4 (17.3%)	4 (10%)	0.649
Precipitating factor	15 (23.8%)	7 (30.4%)	8 (20%)	0.637
The state of seizure				0.264
Awakening	22 (34.9%)	11 (47.8%)	11 (27.5%)
Sleep	4 (6.3%)	1 (4.3%)	3 (7.5%)
Both awake and sleep	37 (58.7%)	11 (47.8%)	26 (65%)
Focal discharge	41 (65.0%)	15 (65.2%)	26 (65%)	0.986
Discharge frequency				0.865
S/PS-SW>4Hz	43 (68.2%)	16 (69.6%)	27 (67.5%)
S/PS-SW<4Hz	20 (31.7%)	7 (30.4%)	13 (32.5%)
Epileptiform runs ≥3 s	41 (65.0%)	17 (73.9%)	14 (35%)	0.003
PCR	2 (3.1%)	1 (4.3%)	1 (2.5%)	0.601
PPR	13 (20.6%)	5 (21.7%)	8 (20%)	1.000
Eye closure Sensitivity	2 (3.1%)	1 (4.3%)	1 (2.5%)	0.601

Abbreviations: MS, myoclonic seizures; GTCS, generalized tonic-clonic seizures; AS, absence seizures; PCR, photo-convulsionresponse; PPR, photoparoxysmal responses.

Table 3 Independent Risk Factors for No Remission

	P	OR	CI
Onset age <16	0.041	4.408	1.0–15.5
Febrile seizures	0.049	6.439	1.0–41.0
Epileptiform runs ≥3 s	0.004	6.807	1.8–25.3

Abbreviations: OR, odds ratio; CI, confidence interval.