The Relationship Between the Neutrophil to Lymphocyte Ratio, The Platelet to Lymphocyte Ratio, and Cardiac Syndrome X

Figures & data

Table 1 Comparison of General Data Between the Two Groups[n (%)]

Items	CSX Group	Control Group	t/χ^2	p-value
Number of cases	102	102
Age (Years, )	61.25±12.17	61.03±11.92	0.611	0.265
Gender [No.(%)]			0.182	0.670
Male	58(56.86%)	61(59.80%)
Female	44(43.14%)	41(40.20%)
Smoking [No.(%)]			0.314	0.575
Yes	52(50.98%)	48(47.06%)
No	50(49.02%)	54(52.94%)
Diabetes [No.(%)]			0.522	0.470
Yes	11(10.78%)	8(7.84%)
No	91(89.22%)	94(92.16%)
Hypertension [No.(%)]			1.700	0.192
Yes	15(14.71%)	9(8.82%)
No	87(85.29%)	93(91.18%)
Family history of cancer [No.(%)]			0.578	0.447
Yes	10(9.80%)	7(6.86%)
No	92(90.20%)	95(93.14%)
Serum creatinine (μmol/l, )	71.53±6.21	72.24±6.34	0.808	0.420
Alanine aminotransferase (U/L,)	21.51±1.92	21.93±1.87	1.583	0.115
Triglyceride (mmol/l, )	1.21±0.11	1.23±0.12	1.241	0.216

Abbreviation: CSX, cardiac syndrome X.

Table 2 Comparison of ECG Results Between the Two Groups[n (%)]

Group	Number of Cases (n)	ST-Segment Abnormality	ST Segment Normal
CSX Group	102	43 (42.16)	59 (57.84)
Control group	102	7 (6.86)	95 (93.14)
χ^2		34.336
p-value		<0.001

Abbreviations: ECG, electrocardiograph; CSX, cardiac syndrome X.

Table 3 Comparison of NC, LC, PLT, NLR and PLR in Peripheral Blood Between the Two Groups ()

Group	Number of Cases (n)	NC (10^9/L, )	LC (10^9/L, )	PLT (10^9/L, )	NLR [M (Q1, Q3)]	PLR [M (Q1, Q3)]
CSX Group	102	4.08±0.92	1.85±0.34	221.58±33.22	2.22 (1.74, 2.80)	117.19 (104.07, 145.01)
Control group	102	3.15±0.82	2.19±0.39	189.51±32.23	1.41 (1.07, 1.77)	86.76 (73.68, 101.82)
t/z		5.651	2.403	7.842	−8.177	−8.505
p-value		<0.001	0.029	<0.001	<0.001	<0.001

Abbreviations: NC, neutrophil count; LC, lymphocyte count; PLT, platelets; NLR, neutrophil to lymphocyte ratio; PLR, platelet to lymphocyte ratio. CSX, cardiac syndrome X.

Figure 1 The receiver operating curve for the diagnosis of cardiac syndrome X by each indicator.

Table 4 Multivariate Logistic Regression Analysis of CSX Influencing Factors

Independent Variable	Regression Coefficient	Standard Error	Wald χ^2	p-value	OR (95% CI)
Electrocardiograph (Control group = NORMAL ST segment)	1.373	0.321	23.125	<0.001*	3.95 (2.10~7.41)
NLR (Reference group = below 2.21)	1.241	0.313	19.102	<0.001*	3.46 (1.87~6.39)
PLR (Control group = less than 119.77)	1.297	0.311	20.028	<0.001*	3.66 (1.99~6.73)

Note: *P<0.05.

Abbreviations: CSX, cardiac syndrome X; OR, odd ratio; NLR, neutrophil to lymphocyte ratio; PLR, platelet to lymphocyte ratio.