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REVIEW

Pediatric Sepsis Requiring Intensive Care Admission: Potential Structured Follow-Up Protocols to Identify and Manage New or Exacerbated Medical Conditions

, , , &
Pages 1881-1891 | Received 28 May 2023, Accepted 29 Aug 2023, Published online: 16 Sep 2023

Figures & data

Figure 1 PRISMA flow diagram of study identification, screening and selection.

Notes: Identification of studies via databases (left) was completed using Embase and Medline, from which 55 duplicate studies were removed prior to screening. 363 records were screened and 332 did not meet initial inclusion criteria. Remaining 31 reports were fully reviewed and assessed for eligibility, ultimately yielding 8 eligible studies. There was one study identified via other methods (right), which was through manual citation search. A total of 9 studies were included. PRISMA figure adapted from Haddaway NR, Page MJ, Pritchard CC, McGuinness LA. PRISMA2020: An R package and Shiny app for producing PRISMA 2020-compliant flow diagrams, with interactivity for optimised digital transparency and Open Synthesis. Campbell Syst Rev. 2022;18(2):e1230.Citation24 Creative Commons.
Figure 1 PRISMA flow diagram of study identification, screening and selection.

Figure 2 Follow-up intervals & outcomes of included studies.

Notes: Each included study is illustrated in chronological order based on follow-up interval in relation to discharge (with exception of Fitzgerald et al, 2021, which describes a follow-up protocol). This figure shows varying trajectories of recovery after discharge.
Abbreviations: IQ, intelligence quotient; FSS, Functional Status Scale; PCPC, Pediatric Cerebral Performance Category; PICU, Pediatric Intensive Care Unit; POPC, Pediatric Overall Performance Category; VA ECMO, venoarterial extracorporeal membrane oxygenation.
Figure 2 Follow-up intervals & outcomes of included studies.

Table 1 Studies Describing Follow-Up After Pediatric Sepsis Requiring Intensive Care

Figure 3 Screening and Follow-up for PICU Sepsis Survivors.

Notes: Example of screening and follow-up workflow described by Fitzgerald et al, 2021, which stratifies patients based on medical complexity in order to determine most appropriate follow-up provider. Adapted from Fitzgerald JC, Kelly N-A, Hickey C, et al. Implementation of a Follow-Up System for Pediatric Sepsis Survivors in a Large Academic Pediatric Intensive Care Unit. Front Pediatr. 2021;9:691692.Citation23
Abbreviations: PICU, Pediatric Intensive Care Unit; MODS, multiple organ dysfunction syndrome; PSP, Pediatric Sepsis Program; PCP, primary care provider; CHOP, Children’s Hospital of Philadelphia; PT/OT, physical therapy/occupational therapy.
Figure 3 Screening and Follow-up for PICU Sepsis Survivors.