Early Diastolic Peak Velocity of Mitral Valve Annulus and Right Ventricular Systolic Tricuspid Annular Velocity as Predictors in Assessing Prognosis of Patients with Sepsis

Figures & data

Figure 1 (A) Measurement of LVEF value, where LVEF=(EDV-ESV)/EDV%. (B) Method of measurement of mitral annulus contraction velocity (LV-SM). (C) Method of measurement of tricuspid annulus contraction velocity (RV-SM).

Table 1 Comparison of the Primary Infection Site and General Condition Between the Death Group and the Survival Group

Item	Survival Group (67 Cases)	Death Group (33 Cases)	P value
Infection site
Respiratory infection	44	19	0.43
Urinary tract infection	12	3	0.388
Liver and gallbladder infection	7	6	0.444
Gastrointestinal infection	10	5	1.0
Skin soft tissue	3	1	1.0
Central nervous system	1	1	1.0
Other parts	3	2	1.0
General condition
Age/years	67.4±10.6	68.1±11.2	0.75
Male: female/cases	45:22	20:13	0.52
Hypertension	31	17	0.62
Diabetes	28	15	0.73
Coronary heart disease	27	14	0.84
Body mass index (kg/m-2)	22.0±2.2	21.8±2.4	0.74

Figure 2 Chart showing the proportion of different types of septic cardiomyopathy.

Table 2 Comparison of Ultrasound Parameters Between Survival and Deceased Group

Item	Survival Group [n=67]	Deceased Group [n=33]	P value
Diastolic parameters
e’(cm/s)	8.61±0.99	8.01±1.01	0.006
E/e’ ratio	11.96±2.13	12.08±2.01	0.795
Systolic parameters
LV-EF(%)	54.42±6.23	55.13±5.1	0.21
LVDD(mm)	54.32±6.12	52.71±7.41	0.23
LV-Sm(cm/s)	7.93±1.25	8.4±1.85	0.11
RV-Sm(cm/s)	13.69±1.74	12.10±2.47	0.00

Notes: Early diastolic flow peak velocity of mitral valve (E), early diastolic peak velocity of mitral valve annulus (e’), left ventricular ejection fraction (LVEF), left ventricular end-diastolic diameter (LVDD), left ventricular systolic mitral annular velocity (LV-Sm), right ventricular systolic tricuspid annular velocity (RV-Sm).

Table 3 Logistic Regression Analysis of Prognostic Factors in Patients with Sepsis

Indicator	B value	S.E.	Wald	P value	OR value
e’	−0.528	0.23	5.262	0.022	0.59
RV-Sm	−0.418	0.149	7.883	0.005	0.658
Constant	9.050	2.776	10.625	0.001	8516.895

Table 4 The Predictive Value of Ultrasound-Related Indicators for the Prognosis of Patients with Sepsis

Indicator	AUC	95% CI	P value	Optimal Cut-off Value	Sensitivity	Specificity	Youden Index
EM	0.675	0.557,0.793	0.005	8.65	67.70%	71%	0.387
RVSM	0.668	0.556,0.78	0.007	12.85	51.60%	73.9%	0.255

Notes: EM indicated e’; RVSM indicated RV-Sm.

Figure 3 ROC curve analysis of ultrasound-related indicators for predicting the prognosis of patients with sepsis.