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Review

Congenital hypothyroidism: current perspectives

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Pages 91-102 | Published online: 17 Jul 2015

Figures & data

Figure 1 Diagnostic algorithm for congenital hypothyroidism.

Note: Abnormal newborn screening test results or a clinical suspicion of hypothyroidism leads to serum thyroid function tests (typically TSH and free T4) to confirm the diagnosis after which other diagnostic studies can be undertaken to determine the exact underlying etiology.
Adapted from Rastogi MV, LaFranchi SH. Congenital hypothyroidism. Orphanet J Rare Dis. 2010;5:17.Citation16
Abbreviations: T4, thyroxine; TSH, thyroid stimulating hormone; T3, triiodothyronine; CH, congenital hypothyroidism; HPT, hypothalamic-pituitary thyroid; TSHβ, TSH β subunit; MRI, magnetic resonance imaging; yr, years.
Figure 1 Diagnostic algorithm for congenital hypothyroidism.