High frequency of bladder cancer after nephroureterectomy: justification for adjuvant intravesical treatment?

Figures & data

Table 1 Patients’ characteristics

	N	Percentage
Gender
Male	67	73.63
Female	24	26.37
Age (years)
Average	66.4	(SD=11.24)
UTUC grade
High	63	69.23
Low	28	30.77
Stage
Ta	22	24.18
T1	27	29.67
T2	19	20.88
T3	23	25.27
Location
Kidney	52	57.14
Ureter	39	42.86
Treatment
Laparoscopic	43	47.25
Open	48	52.75
Previous bladder cancer
Yes	12	13.19
No	79	86.81
Previous ureteroscopy
Yes	37	40.66
No	54	59.34

Abbreviation: UTUC, upper tract urothelial carcinoma.

Figure 1 Bladder recurrence-free survival according to recurrence grade.

Abbreviations: HG, high grade; LG, low grade.

Table 2 Bladder recurrence univariate model

	Bladder recurrence, n (%)	No bladder recurrence, n (%)	Exact significance (two sided)a
Total	38 (41.8)	53 (58.2)
Gender
Female	7 (29.2)	17 (70.8)
Male	31 (46.3)	36 (53.7)	0.158
Age (years)
<67	20 (45.5)	24 (54.5)
≥67	18 (38.3)	29 (61.7)	0.529
Grade
High	25 (39.7)	38 (60.3)
Low	13 (46.4)	15 (53.6)	0.646
Stage
Ta	13 (59.1)	9 (40.9)
T1	9 (33.3)	18 (66.7)
T2	7 (36.8)	12 (63.2)
T3	9 (39.1)	14 (60.9)	0.289
Location
Kidney	24 (46.2)	28 (53.8)
Ureter	14 (35.9)	25 (64.1)	0.393
Surgical approach
Laparoscopic	18 (41.9)	25 (58.1)
Open	20 (41.7)	28 (58.3)	1
Previous bladder cancer
Yes	5 (41.7)	7 (58.3)
No	33 (41.8)	46 (58.2)	1
Previous ureteroscopy
Yes	18 (48.6)	19 (51.4)
No	20 (37.0)	34 (63.0)	0.288

Notes:

a Chi-square Fisher’s exact test was performed. For variables more than two categorical variables – the asymptotic significance (two-sided) was depicted instead of Fisher’s exact significance.