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Review

The potential of CAR T therapy for relapsed or refractory pediatric and young adult B-cell ALL

, , &
Pages 1573-1584 | Published online: 03 Sep 2018

Figures & data

Figure 1 Molecular structure of chimeric antigen receptor used for CTL019.

Abbreviation: ScFv, single-chain variable fragment; VH, variable heavy chain; VL, variable light chain.
Figure 1 Molecular structure of chimeric antigen receptor used for CTL019.

Table 1 Summary of results reported from CD19 CAR T-cell pediatric clinical trials

Table 2 LD regimens used in completed pediatric trials of CD19 CAR T-cells

Figure 2 B-cell antigens used as targets for chimeric antigen receptor T cells.

Abbreviation: TSLPR, thymic stromal lymphopoietin receptor.
Figure 2 B-cell antigens used as targets for chimeric antigen receptor T cells.

Table 3 Open pediatric trials using CD19 CAR T-cells (as of April 2018)