Adequate nutrition status important for bone mineral density improvement in a patient with anorexia nervosa

Figures & data

Table 1 Changes in serum TP, Alb, and ALP

OP	0 M	2 M	1 Y	2 Y	2.5 Y	3 Y	Unit	Reference
TP	6.6	6.5	6.5	6.8	5.9	4.9	g/dL	6.6–8.3
Alb	4.3	4.3	4.3	4.5	3.9	3.4	g/dL	3.7–4.9
ALP	1,187	1,092	307	215	177	124	U/L	105–368

Abbreviations: Alb, albumin; ALP, alkaline phosphatase; M, month(s); OP, observational period; TP, total protein; Y, year(s).

Table 2 Changes in serum BAP, urinary NTX, 1, serum 25(OH)₂D₃, 25(OH)D₃, DPD, ucOC, and TRACP-5b

	0 M	2 M	1 Y	2 Y	2.5 Y	3 Y	Unit	Reference
BAP	212.0	228.0	55.0	29.1	22.6	11.6	U/L	9.6–35.4
Urinary NTX	226.0	276.2	152.9	92.5	118.2	–	nmol BCE/mmol Cr	95–54.3
1,25(OH)2D3	–	35.1	43.3	–	–	–	pg/mL	20–60
25(OH)D3	–	–	–	–	–	5.0	ng/mL	7–41
DPD	–	–	–	–	–	11.7	nmol BCE/mmol Cr	2.8–7.6
ucOC	–	–	–	–	–	0.38	ng/mL	<4.5
TRACP-5b	–	–	–	–	–	149	mU/dL	120–420

Abbreviations: BAP, bone alkaline phosphatase; DPD, deoxypyridinoline; M, month(s); NTX, N-terminal telopeptide of type-I collagen; TRACP, tartrate-resistant acid phosphatase; ucOC, undercarboxylated osteocalcin; Y, year(s).

Figure 1 L-BMD (0.358 g/cm²; T-score = −6.3) prior to treatment.

Note: At 3 years of therapy, it was 0.647 g/cm² (T-score = −2.4; 57.4% increase).
Abbreviations: BMD, bone mineral density; L-BMD, lumbar 1–4 BMD.

Figure 2 Total hip BMD (0.411 g/cm²; T-score = −4.4) prior to treatment.

Note: At 3 years of therapy, it was 0.648 g/cm² (T-score = −3.5; 81% increase).
Abbreviation: BMD, bone mineral density.