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Therapeutics and Clinical Risk Management Volume 14, 2018 - Issue
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Original Research

Fluid resuscitation in critically ill patients: a systematic review and network meta-analysis

Chao Liu1 Department of Critical Care Medicine, Chinese People’s Liberation Army General Hospital, Beijing, People’s Republic of China, [email protected]
,
Zhi Mao1 Department of Critical Care Medicine, Chinese People’s Liberation Army General Hospital, Beijing, People’s Republic of China, [email protected]
,
Pan Hu1 Department of Critical Care Medicine, Chinese People’s Liberation Army General Hospital, Beijing, People’s Republic of China, [email protected]
,
Xin Hu1 Department of Critical Care Medicine, Chinese People’s Liberation Army General Hospital, Beijing, People’s Republic of China, [email protected]
,
Hongjun Kang1 Department of Critical Care Medicine, Chinese People’s Liberation Army General Hospital, Beijing, People’s Republic of China, [email protected]
,
Jie Hu1 Department of Critical Care Medicine, Chinese People’s Liberation Army General Hospital, Beijing, People’s Republic of China, [email protected]
,
Zhifang Yang2 Beijing Institute of Pharmacology and Toxicology, Beijing, People’s Republic of China
,
Penglin Ma3 Department of Critical Care Medicine, the 309th Hospital of Chinese People’s Liberation Army, Beijing, People’s Republic of China, [email protected]Correspondence[email protected]
&
Feihu Zhou1 Department of Critical Care Medicine, Chinese People’s Liberation Army General Hospital, Beijing, People’s Republic of China, [email protected];4 National Clinical Research Center for Kidney Diseases, Chinese People’s Liberation Army General Hospital, Beijing, People’s Republic of China, [email protected]Correspondence[email protected]
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Pages 1701-1709 | Published online: 12 Sep 2018

Figures & data

Figure 1 Study selection.

Figure 1 Study selection.

Figure 2 Network of eligible comparisons for mortality.

Notes: (A) Balanced crystalloid; (B) 4% albumin; (C) hypertonic saline; (D) low-molecular-weight hetastarch; (E) high-molecular-weight hetastarch; (F) 0.9% sodium chloride; (G) dextran; (H) gelatin; (I) 20% albumin.
Figure 2 Network of eligible comparisons for mortality.

Figure 3 Network meta-analysis of mortality.

Note: Data presented as OR (95% CrI).
Abbreviations: ALB, albumin; BC, balanced crystalloid; Crl, credibility interval; DEX, dextran; GEL, gelatin; H-HES, high-molecular-weight hetastarch; HS, hypertonic saline; L-HES, low-molecular-weight hetastarch; NS, 0.9% sodium chloride.
Figure 3 Network meta-analysis of mortality.

Figure 4 The ranking of resuscitation fluid based on the cumulative probability plots and SUCRAs.

Abbreviations: ALB, albumin; BC, balanced crystalloid; DEX, dextran; GEL, gelatin; H-HES, high-molecular-weight hetastarch; HS, hypertonic saline; L-HES, low-molecular-weight hetastarch; NS, 0.9% sodium chloride; SUCRA, surface under the cumulative ranking curve.
Figure 4 The ranking of resuscitation fluid based on the cumulative probability plots and SUCRAs.

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