Steroid response pattern and outcome of pediatric idiopathic nephrotic syndrome: a single-center experience in northwest Iran

Figures & data

Figure 1 Age distribution of 165 patients with idiopathic nephrotic syndrome.

Table 1 Comparison of characteristics of INS between boys and girls

Variable	Boys	Girls	P value	Total
Number (%)	110 (66.7%)	55 (33.3%)	–	165 (100%)
Hematuria	19 (17.3%)	21 (38.2%)	P = 0.01	40 (24.2%)
Hypertension	12 (10.9%)	7 (12.7%)	P = 0.46	19 (11.6%)
Steroid resistance	18 (16.4%)	23 (42%)	P = 0.005	41 (24.8%)
Progression to ESRD	4 (3.6%)	5 (9%)	P = 0.14	9 (5.4%)
Mortality	1 (0.9%)	6 (10.9%)	P = 0.09	7 (4.4%)

Abbreviations: ESRD, end-stage renal disease; INS, idiopathic nephrotic syndrome.

Table 2 Comparison of children with steroid-responsive and steroid-resistant idiopathic nephrotic syndrome

Variable	Steroid sensitive	Steroid resistant	P value
Number (%)	124 (75.2%)	41 (24.8%)	–
Boys	91 (73.4%)	19 (46.3%)	–
Girls	33 (26.6%)	22 (53.7%)	P = 0.005
Hematuria	19 (17.3%)	21 (51.2%)	P = 0.001
Hypertension	13 (10.5%)	6 (14.6%)	P = 0.3
Mean age (years)	4.6 ± 2.4	5.8 ± 3.2	P = 0.017
Mean 24-hour urine protein (mg)	3190.3 ± 322.34	4157.78 ± 448.86	P = 0.11