Analgesic Effect of Serratus Anterior Plane Block After Thoracoscopic Surgery: A Randomized Controlled Double-Blinded Study

Figures & data

Table 1 Comparison of General Clinical Data Between Two Groups

Group	N	Male/Female (N)	Age (Years) (Mean±SD)	BMI (kg/m^2) (Mean±SD)	Operation Time (min) (Mean±SD)
Control	30	17/13	58.23±9.03	23.80±2.95	98.23±27.88
SAPB	30	15/15	56.20±7.20	24.47±2.87	107.73±27.16
P		0.612	0.339	0.378	0.186

Notes: Data were analyzed by t-test; continuous variables of normal distribution are expressed as mean ± standard deviation (SD).

Figure 1 Flow diagram of the study design.

Abbreviation: SAPB, serratus anterior plane block

Figure 2 Kaplan–Meier curves comparing time to VAS =4 within 48 hrs after operation in two groups (patients were censored if VAS did not reach 4 or above within 48 hrs after surgery); survival curve analysis (log-rank test): P=0.008.

Abbreviations: SAPB, serratus anterior plane block; VAS, visual analogue scale.

Table 2 The Number of Patients Requiring Additional Analgesics at Different Time Points After Surgery (N)

Group	6hrs	12hrs	24hrs	48hrs
Control	11	15	3	1
SAPB	3	6	3	2
P	0.03	0.03	1	1

Note: The data were analyzed by Fisher’s exact test.

Table 3 Intraoperative Remifentanil and Propofol Dose (mean±SD)

Group	N	Intraoperative Remifentanil Dose Operation (μg)	Intraoperative Propofol Dose (mg)
Control	30	242.76±98.42	762.24±102.61
SAPB	30	250.98±65.84	748.58±71.61
P		0.705	0.552

Notes: Data were analyzed by t-test, and continuous variables of normal distribution are expressed as means± standard deviation (SD).

Table 4 Adverse Reactions

Group	Nausea and Vomiting[n(%)]
Control	3 (10%)
SAPB	4 (13%)
P	1.00

Notes: Data were analyzed by Fisher’s exact test, and the categorical variables are presented as n (%).