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ORIGINAL RESEARCH

Analysis of Patients’ Characteristics and Treatment Profile of People Who Use Drugs (PWUDs) with and without a Co-Diagnosis of Viral Hepatitis C: A Real-World Retrospective Italian Analysis

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Pages 645-656 | Received 14 Mar 2023, Accepted 23 Jul 2023, Published online: 04 Aug 2023

Figures & data

Figure 1 Flow-chart reporting study population identification and derived cohorts: (A) study on the overall inclusion period; (B) study on the inclusion period divided into before and after 2017.

Figure 1 Flow-chart reporting study population identification and derived cohorts: (A) study on the overall inclusion period; (B) study on the inclusion period divided into before and after 2017.

Table 1 Baseline Characteristics of PWUD Population, Overall and Stratified in PWUD-HCV+ and PWUD-HCV

Table 2 Baseline Characteristics of PWUD-HCV+ Patients, treated and Untreated with DAA-Anti HCV Medications

Table 3 Main Causes of Previous Hospitalization in PWUDs Stratified According to the Presence/Absence of HCV and, Among HCV+, to the Presence/Absence of DAA Treatment

Table 4 Number of Drugs Prescribed (Excluding DAAs) During the First Year of Follow-Up (Index-Date Included); (A) Overall PWUDs and in Patients Stratified by the HCV Diagnosis; (B) Overall PWUD-HCV+ Population, DAA-Treated and Untreated Patients

Figure 2 Treatment evaluation in overall PWUD patients and in those stratified by the HCV co-diagnosis during the first year of follow-up: distribution according to the drug ATC first level identification code (excluding DAAs).

Notes: Code contents: A, Alimentary tract and metabolism; B, Blood and blood forming organs; C, Cardiovascular system; D, Dermatological; E, Genito-urinary system and sex hormones; F, Systemic hormonal preparations; G, Anti-infective for systemic use; H, Antineoplastic and immunomodulating agents; I, Musculo-skeletal system; J, Nervous system; K, Antiparasitic products; L, Respiratory system; M, Sensory organs; N, Various.
Figure 2 Treatment evaluation in overall PWUD patients and in those stratified by the HCV co-diagnosis during the first year of follow-up: distribution according to the drug ATC first level identification code (excluding DAAs).

Figure 3 Treatments evaluation in overall PWUD patients and in those stratified by the HCV co-diagnosis during the first year of follow-up: distribution according to the drug ATC second level identification code (excluding DAAs).

Notes: Code contents: A02, Drugs for acid-related disorders; A05, Bile and liver therapy; A06, Drugs for constipation; A07, Antidiarrheals, intestinal anti-inflammatory/anti-infective agents; A10, Drugs used in diabetes; A11, Vitamins; C02, Antihypertensives; C03, Diuretics; C07, Calcium channel blockers; C08, Beta blocking agents; C09, Agents acting on the renin–angiotensin system; C10, Lipid modifying agents; N02, Analgesics; N03, Antiepileptics; N04, Anti-Parkinson drugs; N05, Psycholeptics; N06, Psychoanaleptics; N07, Other nervous system drugs.
Figure 3 Treatments evaluation in overall PWUD patients and in those stratified by the HCV co-diagnosis during the first year of follow-up: distribution according to the drug ATC second level identification code (excluding DAAs).

Table 5 Analysis of Healthcare Resources Consumption During First Year of Follow-Up Period