The effect of eradicating Helicobacter pylori on idiopathic central serous chorioretinopathy patients

Figures & data

Table 1 Baseline demographic characteristics in the two study groups

	Active treatment group (n = 27)	Control group (n = 26)	P-value
Age (years)
Mean ± SD	35.66 ± 5.47	34.85 ± 5.53	0.57
Range	22–48	25–47
Gender
Male:female	27:5	26:5	0.83
Interval between the beginning of symptoms and treatment (days)
Mean ± SD	9.83 ± 7.42	10.32 ± 6.52	0.68
Range	3–20	4–21

Abbreviations: n, number; SD, standard deviation.

Table 2 The disappearance rate of SRF between the two study groups

	2 weeks	4 weeks	8 weeks	12 weeks
Active treatment group	3.7% (1/27)	25.9% (7/27)	40.7% (11/27)	63.0% (17/27)
Control group	0% (0/26)	15.4% (4/26)	34.6% (9/26)	50.0% (13/26)
P-value	0.51	0.17	0.20	0.14

Note: Comparisons between the two groups using Fisher’s exact test.

Abbreviation: SRF, subretinal fluid.

Table 3 Changes in BCVA between the two study groups

	Active treatment group (n = 27)	Control group (n = 26)	P-value
BCVA letter score at baseline
Mean ± SD	74.0 ± 3.9	74.2 ± 3.7	0.946
Range	68–80	67–79
2-week follow-up visit
Mean ± SD	73.8 ± 4.1	74.5 ± 3.2	0.530
Range	68–81	68–80
4-week follow-up visit
Mean ± SD	75.3 ± 3.5	74.9 ± 4.2	0.244
Range	69–83	70–81
8-week follow-up visit
Mean ± SD	77.9 ± 3.2	76.3 ± 3.8	0.112
Range	70–83	70–82
12-week follow-up visit
Mean ± SD	80.8 ± 2.9	77.6 ± 2.6	0.108
Range	71–85	71–82

Notes: Within-group comparison using Student’s independent t-test. P-values <0.05 were considered to be statistically significant.

Abbreviations: BCVA, best-corrected visual acuity; n, number; SD, standard deviation.

Table 4 Changes in central retinal sensitivity between the two study groups

	Active treatment group (n = 27)	Control group (n = 26)	P-value
Retinal sensitivity at the baseline (dB)
Mean ± SD	15.5 ± 0.6	15.4 ± 0.5	0.830
Range	14.3–15.9	14.5–15.8
2-week follow-up visit
Mean ± SD	15.7 ± 0.7	15.5 ± 0.8	0.645
Range	14.3–16.9	14.2–16.9
4-week follow-up visit
Mean ± SD	15.9 ± 0.5	15.7 ± 0.6	0.328
Range	14.9–17.0	14.5–16.9
8-week follow-up visit
Mean ± SD	16.3 ± 0.6	15.8 ± 0.8	0.336
Range	15.0–17.4	14.5–17.3
12-week follow-up visit
Mean ± SD	18.3 ± 1.1	16.1 ± 0.7	0.042
Range	16.3–19.0	15.1–17.8

Notes: Within-group comparison using Student’s t-test. P-values <0.05 were considered to be statistically significant.

Abbreviations: n, number; SD, standard deviation.