Staphylococcus aureus bacteremias following liver transplantation: a clinical analysis of 20 cases

Figures & data

Table 1 Demographic, laboratory, and clinical characteristics of 20 liver recipients with Staphylococcus aureus bacteremias

Characteristics	Value
Age, mean years ± standard deviation	42.7±14.5
Sex, number of males/number of females	19/1
Temperature of 38°C or greater	12/20
Nosocomial origin	20/20
Inappropriate antimicrobial use	7/20
Septic shock	9/20
Site of primary infection, number of cases (%)
Lung	11 (55)
Intra-abdominal/biliary	6 (30)
Unknown	3 (15)
Time of bacteremia onset (post-transplant), number of cases (%)
≤2 weeks	16 (80)
>2 weeks	4 (20)
MRSA, number of cases (%)
Yes	16 (80)
No	4 (20)
Type of organisms, number of cases (%)
Monomicrobial	7 (35)
Polymicrobial	13 (65)
Laboratory variables, number of cases (%)
Platelet count <50,000/mm^3	10 (50)
Lymphocyte count <300/mm^3	6 (30)
Albumin level <30 mg/dL	3 (15)
WBC count >15,000/mm^3	8 (40)
Creatinine level >1.5 mg/dL	5 (25)
Related mortality	9 (45)

Abbreviations: MRSA, methicillin-resistant Staphylococcus aureus; WBC, white blood cell.

Table 2 Resistance of S. aureus to eleven antibiotics

Antibiotics	ERY	CC	LVF	SXT	AN	PEN	RA	OX	VAN	TEC	LZD
S. aureus (20)	18 (90)	14 (70)	10 (50)	15 (75)	6 (30)	19 (95)	2 (10)	16 (80)	0 (0)	0 (0)	0 (0)

Notes: Data presented as number of cases (%).

Abbreviations: S. aureus, Staphylococcus aureus; ERY, erythromycin; CC, clindamycin; LVF, levofloxacin; SXT, trimethoprim-sulfamethoxazole; AN, amikacin; PEN, penicillin; RA, rifampicin; OX, oxacillin; VAN, vancomycin; TEC, teicoplanin; LZD, linezolid.