Patient-perceived health-related quality of life before and after laparoscopic aortobifemoral bypass

Figures & data

Table 1 Clinical characteristics of 50 patients operated with LABFB

Variables	LABFB, N=50
Age in years	62 (59–67)a
Gender: female/male	23/27
BMI	24.2 (22.8–25.7)a
Hypertension	38 (76%)
CHD	17 (34%)
Dyslipidemia	30 (60%)
Diabetes mellitus	6 (12%)
Tobacco use	37 (74%)
ASA category 3	36 (72%)
COPD	14 (28%)
Prior vascular intervention/operation	22 (44%)
Run-off artery stenosis/occlusion	21 (42%)
Prior laparotomy	14 (28%)
Concomitant operation	35 (70%)

Note:

a Median and interquartile range.

Abbreviations: ASA category 3, the American Society of Anesthesiologists category 3; BMI, body mass index; CHD, coronary heart disease; COPD, chronic obstructive pulmonary disease; LABFB, laparoscopic aortobifemoral bypass.

Table 2 Scale reliability and homogeneity estimates of SF-36 response at all time points (preoperative, 1, 3 and 6 months postoperatively) in 50 patients operated with laparoscopic aortobifemoral bypass for TASC II type D lesions

Scale	Number of items	Cronbach’s alpha
Physical functioning	10	0.937
Role physical	4	0.897
Bodily pain	2	0.848
General health	5	0.778
Vitality	4	0.867
Social functioning	2	0.867
Role emotional	3	0.857
Mental health	5	0.800

Abbreviations: SF-36, Short-Form 36; TASC, Trans-Atlantic Inter-Society Consensus.

Figure 1 Changes in the scores (observed mean values) of individual domains in the SF-36, in 50 patients before and after laparoscopic aortobifemoral bypass for the treatment of aortoiliac occlusive disease (Trans Atlantic Inter-Society Consensus II, type D lesions).

Notes: Changes in summary scores PCS and MCS are also illustrated. The vertical bars represent 95% confidence interval.
Abbreviations: BP, bodily pain; GH, general health; MCS, mental component score; MH, mental health; PF, physical functioning; PCS, physical component score; RP, role limitations due to physical problems; RE, role limitations due to emotional problems; SF, social functioning; SF-36, Short-Form 36; VT, vitality.

Table 3 Results of the linear mixed-effect regression analysis (univariate and multivariate) of the physical component of the SF-36, PF, at 1, 3 and 6 months after laparoscopic aortobifemoral bypass of 50 patients for aortoiliac occlusive disease, TASC II, type D lesions

Time	Univariate			Multivariate
	Coefficient	95% Confidence interval	P-value	Coefficient	95% Confidence interval	P-value
Time, preop	Ref			Ref
1 month	41.6	35.33, 47.82	0.001	41.5	35.17, 47.77	0.001
3 months	52.0	44.96, 58.97	0.001	51.9	45.01, 58.75	0.001
6 months	52.6	45.14, 60.09	0.001	52.1	44.86, 59.38	0.001
Smoking (yes vs no)	7.5	−0.97, 15.96	0.082	8.1	1.12, 15.18	0.023
Blood loss (dL)	−0.9	−1.35, −0.43	0.001	−0.8	−1.17, −0.32	0.001
Concomitant operation (yes vs no)	−10.9	−18.59, −3.20	0.01	−9.8	−16.54, −2.98	0.005
ASA (category 3 vs category 1+2)	−6.1	−14.21, 2.03	0.141
Length of hospital stay (days)	−0.5	−1.00, −0.05	0.030
Aorta clamping (minutes)	0.14	−0.03, 0.31	0.107
Age (years)	−0.2	−0.73, 0.37	0.516
Gender (male/female)	0.4	−7.25, 8.10	0.914
Operation time (minutes)	0.03	−0.10, 0.04	0.464
Prior vascular operation or intervention	3.5	−4.13, 11,17	0.367

Abbreviations: ASA, the American Society of Anesthesiologists category; PF, physical functioning; Ref, reference; SF-36, Short Form-36; TASC, Trans-Atlantic Inter-Society Consensus.

Table 5 Results of the linear mixed-effect regression analysis (univariate and multivariate) of the physical component of the SF-36, bodily pain, at 1, 3 and 6 months after laparoscopic aortobifemoral bypass of 50 patients for aortoiliac occlusive disease, TASC II, type D lesions

Time	Univariate
	Coefficient	95% Confidence interval	P-value
Smoking	3.3	−6.72, 13.31	0.519
Blood loss (dL)	−0.6	−1.18, −0.04	0.035
Concomitant operation (yes vs no)	−6.7	−16.11, 2.64	0.159
ASA (category 3 vs category 1+2)	−1.8	−11.40, 7.76	0.710
Length of hospital stay (days)	−0.4	−0.91, 0.20	0.205
Aorta clamping (minutes)	0.02	−0.18, 0.21	0.867
Age (years)	0.3	−0.37, 0.90	0.417
Gender (male/female)	2.1	−6.75, 10.90	0.645
Operation time (minutes)	0.03	−0.05, 0.11	0.465
Prior vascular operation or intervention	4.5	−4.32, 13.34	0.317

Abbreviations: ASA, the American Society of Anesthesiologists category; SF-36, Short Form-36; TASC, Trans-Atlantic Inter-Society Consensus.

Table 4 Results of the linear mixed-effect regression analysis (univariate and multivariate) of the physical component of the SF-36, role physical, at 1, 3 and 6 months after laparoscopic aortobifemoral bypass of 50 patients for aortoiliac occlusive disease, TASC II, type D lesions

Time	Univariate			Multivariate
	Coefficient	95% Confidence interval	P-value	Coefficient	95% Confidence interval	P-value
Time, preop	Ref			Ref
1 month	50.1	38.83, 61.39	0.001	49.9	38.64, 61.12	0.001
3 months	66.65	54.60, 78.71	0.001	66.5	54.33, 78.75	0.001
6 months	59.3	46.62, 72.10	0.001	59.0	46.10, 71.90	0.001
Smoking (yes vs no)	14.31	−0.10, 28.72	0.052	15.6	3.01, 28.25	0.01
Blood loss (dL)	−1.0	−1.79, −0.11	0.027
Concomitant operation (yes vs No)	−21.57	−34.37, −8.76	0.001	−20.5	−33.12, −7.88	0.001
ASA (category 3 vs 1+2)	−13.8	−27.39, −0.11	0.048
Length of hospital stay (days)	−0.4	−1.19, 0.47	0.390
Aorta clamping (minutes)	0.1	−0.21, 0.38	0.576
Age (years)	−0.01	−1.0, 1,0	0.983
Gender (male/female)	0.8	−12.36, 14.00	0.903
Operation time (minutes)	−0.1	−0.18, 0.06	0.350
Prior vascular operation or intervention	3.3	−9.93, 16.48	0.627

Abbreviations: ASA, the American Society of Anesthesiologists category; Ref, reference; SF-36, Short Form-36; TASC, Trans-Atlantic Inter-Society Consensus.

Table 6 Results of the linear mixed-effect regression analysis (univariate and multivariate) of PCS at 1, 3 and 6 months after laparoscopic aortobifemoral bypass of 50 patients for aortoiliac occlusive disease, TASC II, type D lesions

Time	Univariate			Multivariate
	Coefficient	95% Confidence interval	P-value	Coefficient	95% Confidence interval	P-value
Time, preop	Ref			Ref
1 month	15.6	13.10, 18.10	0.001	15.5	13.00, 18.04	0.001
3 months	20.3	17.10, 23.01	0.001	20.3	17.60, 22.94	0.001
6 months	19.1	16.20, 21.90	0.001	18.9	16.11, 21.74	0.001
Smoking (yes vs no)	3.5	−0.10, 7.10	0.056	3.8	0.63, 6.88	0.02
Blood loss (dL)	−0.3	−0.53, −0.13	0.001	−0.3	−0.46, −0.09	0.004
Concomitant operation (yes vs no)	−4.1	−7.40, −0.70	0.018	−3.7	−6.72, 0.69	0.016
ASA (category 3 vs 1+2)	−3.6	−7.01, −0.25	0.035
Length of hospital stay (days)	−0.11	−0.32, 0.09	0.276
Aorta clamping (minutes)	0.02	−0.05, 0.09	0.596
Age (years)	−0.004	−0.24, 0.23	0.977
Gender (male/female)	0.7	−2.60, 3.93	0.689
Operation time (minutes)	0.002	−0.03, 0.03	0.903
Prior vascular operation or intervention	1.8	−1.50, 5.01	0.289

Abbreviations: ASA, the American Society of Anesthesiologists category; PCS, Physical Component Score; Ref, reference; SF-36, Short Form-36; TASC, Trans-Atlantic Inter-Society Consensus.

Table 7 Results of the linear mixed-effect regression analysis (univariate and multivariate) of MCS at 1, 3 and 6 months after laparoscopic aortobifemoral bypass of 50 patients for aortoiliac occlusive disease, TASC II, type D lesions

Time	Univariate
	Coefficient	95% Confidence interval	P-value
Time, preop	Ref
1 month	2.2	−1.25, 5.70	0.209
3 months	3.7	−0.10, 7.44	0.054
6 months	4.4	0.40, 8.35	0.031
Smoking (yes vs no)	2.4	−1.97, 6.84	0.279
Blood loss (dL)	−0.3	−0.51, 0.004	0.054
Concomitant operation (yes vs no)	−3.0	−7.19, 1.13	0.153
Length of hospital stay (days)	−0.3	−0.50, −0.02	0.034
Aorta cross-clamping (minutes)	0.1	−0.02, 0.16	0.126
ASA (category 3 vs 1+2)	−1.0	−5.25, 3.23	0.642
Age (years)	−0.03	−0.31, 0.26	0.852
Gender (male/female)	0.3	−3.61, 4.23	0.877
Operation time (minutes)	−0.02	−0.06, 0.01	0.231
Prior vascular operation or intervention	0.6	−3.34, 4.53	0.768

Abbreviations: ASA, the American Society of Anesthesiologists category; MCS, Mental Component Score; Ref, reference; SF-36, Short Form-36; TASC, Trans-Atlantic Inter-Society Consensus.