Doppler study of cerebral arteries in hypercholesterolemia

Figures & data

Table 1 Patients’ demographic data and clinical characteristics (mean ± standard deviation)

	Hypercholesterolemia group (n = 30)	Control group (n = 30)	Pvalue
Gender (male:female)	14:16	14:16	1.00
Age (years)	54.66 (36–70)	51.60 (30–75)	0.55
Hypertension, n (%)	13 (43.3)	8 (26.6)	0.27
Diabetes mellitus, n (%)	4 (13.3)	5 (16.6)	1.00
Smoker, n (%)	11 (36.6)	4 (13.3)	0.07
Obesity, n (%)	8 (26.6)	5 (16.6)	0.53

Table 2 Transcranial Doppler indices of the intracranial artery (mean ± standard deviation)

Artery	Index	Hypercholesterolemia group (n = 30)	Control group (n = 30)	Pvalue
MCA	MV	60.5 ± 18.8	56.2 ± 9.2	0.98
	PI	0.82 ± 0.17	0.78 ± 0.15	0.45
	RI	0.53 ± 0.08	0.51 ± 0.05	0.46
ACA	MV	46.4 ± 22.3	63.9 ± 10.1	0.86
	PI	0.76 ± 0.35	0.83 ± 0.5	0.70
	RI	0.46 ± 0.19	0.48 ± 0.14	0.45
ICA	MV	22 ± 17.9	28.7 ± 9.9	0.15
	PI	0.59 ± 0.45	0.83 ± 0.27	0.08
	RI	0.36 ± 0.26	0.51 ± 0.15	0.06
PCA1	MV	38.9 ± 12.4	37 ± 9.6	0.91
	PI	0.08 ± 0.22	0.76 ± 0.2	0.43
	RI	0.5 ± 0.11	0.49 ± 0.1	0.44
PCA2	MV	40.1 ± 13	38.6 ± 11.3	0.51
	PI	0.79 ± 0.21	0.79 ± 0.16	0.51
	RI	0.5 ± 0.11	0.53 ± 0.12	0.75
VA	MV	35.2 ± 11.6	32.9 ± 8.9	0.60
	PI	0.82 ± 0.17	0.76 ± 0.13	0.21
	RI	0.52 ± 0.06	0.51 ± 0.08	0.32
BA	MV	41.8 ± 13.2	41.2 ± 11.3	0.62
	PI	0.85 ± 0.17	0.76 ± 0.22	0.14
	RI	0.54 ± 0.06	0.49 ± 0.11	0.12

Abbreviations: MCA, middle cerebral artery; ACA, anterior cerebral artery; ICA, internal carotid artery; PCA1, first segment of posterior cranial artery; PCA2, second segment of posterior cranial artery; VA, vertebral artery; BA, basilar artery; MV, mean blood flow velocity; PI, pulsatility index; RI, resistive index.

Table 3 Transcranial Doppler indices of intracranial arteries in LDL > 180 mg/dL versus < 180 mg/dL groups (mean ± standard deviation)

Artery	Index	LDL >180 mg/dL	LDL <180 mg/dL	Pvalue
MCA	MV	56.8 ± 12.56	59.1 ± 15.9	0.54
	PI	0.79 ± 0.19	0.81 ± 0.15	0.50
	RI	0.52 ± 0.09	0.52 ± 0.05	0.41
ACA	MV	44.5 ± 23.06	60.4 ± 88	0.69
	PI	0.71 ± 0.35	0.84 ± 0.46	0.23
	RI	0.44 ± 0.19	0.49 ± 0.15	0.27
ICA	MV	19.3 ± 16	28.4 ± 13.4	0.04*
	PI	0.56 ± 0.44	0.79 ± 0.34	0.055
	RI	0.34 ± 0.26	0.48 ± 0.19	0.02*
PCA1	MV	36 ± 13	38.9 ± 10	0.12
	PI	0.74 ± 0.24	0.8 ± 0.2	0.25
	RI	0.48 ± 0.01	0.51 ± 0.1	0.26
PCA2	MV	39.8 ± 15.4	39.1 ± 10.4	0.96
	PI	0.74 ± 0.23	0.82 ± 0.16	0.22
	RI	0.48 ± 0.12	0.54 ± 0.11	0.18
VA	MV	34.7 ± 10	33.6 ± 10.6	0.66
	PI	0.78 ± 0.15	0.8 ± 0.15	0.55
	RI	0.51 ± 0.05	0.52 ± 0.08	0.45
BA	MV	39.7 ± 9.1	42.30 ± 13.6	0.23
	PI	0.81 ± 0.16	0.81 ± 0.22	0.80
	RI	0.52 ± 0.06	0.51 ± 0.1	0.80

Note:

* Statistically significant (P < 0.05).

Abbreviations: MCA, middle cerebral artery; ACA, anterior cerebral artery; ICA, internal carotid artery; PCA1, first segment of posterior cranial artery; PCA2, second segment of posterior cranial artery; VA, vertebral artery; BA, basilar artery; MV, mean blood flow velocity; PI, pulsatility index; RI, resistive index.