The Outcomes of PBMV in Pregnancy, and When is the Best Time?

Figures & data

Table 1 Demographic and Baseline Data of Studied Patients

		Cases (N=44)
Age (years)	Mean +SD	29.51 ± 6.22
	Range	21–35
Gestational age (weeks)	Mean +SD	23.27 ± 7.11
	Range	(16–30)
NYHA classification	III	40	90.9%
	IV	4	9.1%
Prior surgical open commissurotomy		5	11.4%
Atrial fibrillation		4	9.1%
Sinus rhythm		40	90.9%
Wilkin’s score	≤8	32	72.7%
	>8	12	27.3%

Abbreviations: N, number; SD, standard deviation; NYHA, New York Heart Association.

Table 2 Mitral Regurge Before and After the PBMV Procedure

		Before (N=44)	After (N=44)	P value
		No (%)	No (%)
Mitral regurge	No	28 (63.6%)	16 (36.8%)	<0.001*
	Grade I	12 (27.2%)	22 (50%)
	Grade II	4 (9%)	6 (13.6%)

Notes: P value, probability value; *Statistically significant.

Abbreviations: MR, mitral regurge; N, number; SD, standard deviation; PBMV, percutaneous balloon mitral valvuloplasty.

Table 3 Echocardiographic Parameters Before and After the PBMV Procedure

	Before (N=44)	After (N=44)	P value
	Mean +SD	Mean +SD
Pulmonary artery systolic pressure (mmHg)	55.43 ± 23.4	33.63 ± 11.40	<0.001*
LA pressure (mmHg)	25.16 ± 7.10	11.27 ± 4.61	<0.001*
Trans-valvular pressure gradient (mmHg)	17.22 ± 5.55	8.94 ± 3.75	<0.001*
Mitral valve area (cm^2)	1.12 ± 0.24	2.09 ± 0.46	<0.001*

Notes: P value, probability value; *Statistically significant.

Abbreviations: cm², cubic centimeter; LA, left atrium; mmHg, millimeter mercury; N, number; SD, standard deviation; PBMV, percutaneous balloon mitral valvuloplasty.

Table 4 NYHA Functional Classification Before and After PBMV Procedure

		Before (n=44)	After (n=44)	P value
		No (%)	No (%)
NYHA Class	I	0	6 (13.6%)	<0.001*
	II	0	35 (79.5%)
	III	40 (90.9%)	3 (6.9%)
	IV	4 (9.1%)	0

Notes: P value, probability value; *Statistically significant.

Abbreviations: N, number; SD, standard deviation.

Table 5 Procedure Adverse Outcomes During the Second and Third Trimesters

Obstetric and Fetal Outcomes	PBMV Performed During 2nd Trimester (N=26)	PBMV Performed During 3rd Trimester (N=18)	P-value
	No (%)	No (%)
Preterm labor	1 (3.85%)	5 (27.78%)	0.034
Dead fetus	0 (0%)	3 (16.67%)	0.031
Low birth weight	1 (3.85%)	1 (5.56%)	0.66
Composite adverse outcome	1 (3.85%)	7 (38.89%)	0.005

Notes: P value, probability value; *Statistically significant.

Abbreviations: N, number; PBMV, percutaneous balloon mitral valvuloplasty.

Figure 1 Post procedure adverse obstetric outcomes during the second and third trimesters.