Left ventricular dysfunction in normotensive type II diabetic patients in Port Harcourt, Nigeria

Figures & data

Table 1 Demographic characteristic in subjects and controls

Variable	Subjects	Controls	t-test	P-value
Mean age (years)	50.76 ± 9.13	51.33 ± 7.84	0.460	0.66
Mean BMI (kg/m^2)	26.88 ± 4.73	27.09 ± 4.04	0.330	0.74
Mean SBP (mmHg)	113.87 ± 10.27	117.93 ± 8.81	2.850	0.005
Mean DBP (mmHg)	70.87 ± 7.34	64.64 ± 8.80	0.036	0.036

Abbreviations: BMI, body mass index; DBP, diastolic blood pressure; SBP, systolic blood pressure.

Table 2 Indices of left ventricular structure and function in subjects and controls

Indices	Subjects	Control	P-value
Mean E/A ratio	1.03 ± 0.37	1.44 ± 0.29	0.00
Mean IVRT (milliseconds)	124.91 ± 34.18	114.56 ± 23.64	0.01
Mean DT (milliseconds)	218.49 ± 48.83	212.97 ± 35.34	0.38
Mean E (cm/second)	68.57 ± 16.01	78.16 ± 15.31	0.00
Mean A (cm/second)	69.17 ± 14.67	53.31 ± 11.46	0.00
Mean EF (%)	62.40 ± 8.47	68.52 ± 7.94	0.00
Mean FS (%)	33.76 ± 6.20	38.22 ± 6.10	0.00
Mean LVMI (kg/m^2)	95.17 ± 25.67	85.40 ± 18.0	0.004
Mean RWT	0.475 ± 0.09	0.405 ± 0.07	0.00

Abbreviations: E, peak velocity of early left ventricular filling; A, peak velocity of atrial contraction; DT, deceleration time; EF, ejection fraction; FS, fractional shortening; IVRT, isovolumetric relaxation time; LVMI, left ventricular mass index, RWT, relative wall thickness.

Table 4 Comparison of number of patients and controls with normal and abnormal diastolic filling pattern

Filling pattern	Patient	Control	X^2	P-value
Normal (E/A > 1)	31 (34.4%)	87 (96.7%)	77.16	0.00*
Abnormal Relaxation (E/A < 1)	52 (57.8%)	2 (2.2%)	1.44	0.510
Pseudonormal	6 (6.7%)	1 (1.1%)	3.66	0.118
Restrictive (E/A > 2)	1 (1.1%)	0 (0%)	1.01	1.000

Abbreviations: E/A, the ratio of peak velocities of early left ventricular filling to peak velocity of atrial contraction.

Note:

* = significant P value: P ≤ 0.05.

Table 3 Comparison of number of patients and controls with normal and abnormal left ventricular mass index

Study status	LVMI		X^2	P-value	OR
	Abnormal	Normal
Patient	45 (50%)	45 (50%)	11.4	0.0007*	2.91
Control	23 (25.6%)	67 (74.4%)

Note:

* P-value ≤0.05 is statistically significant.

Abbreviations: OR, odds ratio; LVMI, left ventricular mass index.