Lipid profiles and inflammatory markers after periodontal treatment in children with congenital heart disease and at risk for atherosclerosis

Figures & data

Table 1 Dental clinical evaluation and statistical significance

	SRP (group 1)				FMSRP (group 2)
	1st stage (0)	2nd stage (90 days)	3rd stage (180 days)	Δ (0–180 days)	1st stage (0)	2nd stage (90 days)	3rd stage (180 days)	Δ (0–180 days)
PI (%)	46.81 ±0.70	47.67±0.64	32.65±0.53#	14.16±0.75	39.86±0.40	26.97±0.43#	22.19±0.57#	17.67±1.00
GI (%)	7.61 ±0.17	8.36±0.17	4.13±0.11#	3.48±0.21	5.41±0.12	3.08±0.07#	4.16±0.17#	1.25±0.15*
BOP (%)	20.25±0.56	7.99±0.15#	6.32±0.15#	13.93±0.52	18.03±0.41	5.59±0.24#	4.51 ±0.16#	13.52±0.46
PD (mm)	1.88±0.01	1.53±0.01#	1.39±0.01#	0.49±0.07	1.93±0.01	1.50±0.01#	1.43±0.01#	0.40±0.10
CAL (mm)	1.89±0.01	1.53±0.01#	1.40±0.01#	0.49±0.07	1.93±0.01	1.50±0.01#	1.43±0.01#	0.40±0.10

Notes:

# Statistically significant difference among means within each of the treatment groups at P<0.05

* statistically significant difference between the variation of the means (Δ) of the two treatment groups at P<0.05. Data are expressed as means ± standard error of the mean.

Abbreviations: FMSRP, full-mouth scaling and root planing; PI, plaque index; GI, gingival index; BOP, bleeding on probing; PD, probing depth; CAL, clinical attachment level; SRP, scaling and root planing.

Table 2 Laboratory evaluation and statistical significance

	SRP (group 1)			FMSRP (group 2)
	1st stage (0)	3rd stage (180 days)	Δ (0–180 days)	1st stage (0)	3rd stage (180 days)	Δ (0–180 days)
TC (mg/dL)	153.76±0.60	149.08±0.62#	4.68±0.55	154.80±0.41	149.76±0.53#	5.04±0.54
LDL (mg/dL)	85.83±0.53	90.78±0.70#	−4.95±0.12	85.12±0.46	81.92±0.62	3.20±0.15*
HDL (mg/dL)	51.35±0.32	51.57±0.23	−0.22±0.04	54.37±0.44	53.53±0.44	0.84±0.13
TGs (mg/dL)	82.94±0.86	75.85±0.80#	7.09±0.83	76.93±0.70	71.15±0.61#	5.78±0.86
VLDL (mg/dL)	16.51±0.17	15.21±0.15#	1.30±0.16	15.35±0.14	14.30±0.11#	1.05±0.18
FGN (g/L)	2.71±0.02	2.52±0.01#	0.19±0.02	2.74±0.02	2.35±0.01#	0.39±0.02
CRP (mg/dL)	0.61±0.04	0.20±0.01#	0.41±0.04	0.12±0.01	0.20±0.01	−0.08±0.01
IL-6 (pg/mL)	1.42±0.09	0.85±0.02#	0.57±0.01	0.92±0.02	0.72±0.01#	0.20±0.02
TNF-α (pg/mL)	12.39±0.9	15.79±1.43	−3.38±0.08	13.44±0.70	17.73±1.30	−4.29±0.13

# Statistically significant difference between means within each of the treatment groups at P<0.05

* statistically significant difference between the variation of the means (Δ) of the two treatment groups at P<0.05. Data are expressed as means ± standard error of the mean.

Abbreviations: TC, total cholesterol; HDL, high-density lipoprotein; TGs, triglycerides; VLDL, very-low-density lipoprotein; FGN, fibrinogen; CRP, C-reactive protein; IL, interleukin; TNF, tumor necrosis factor FMSRP, full-mouth scaling and root planing; SRP, scaling and root planing; LDL, low-density lipoprotein.