Neurogenic orthostatic hypotension in Parkinson’s disease: evaluation, management, and emerging role of droxidopa

Figures & data

Figure 1 Overlapping causes of symptomatic nOH (Venn diagram): 1) autonomic failure of NE pathways upon standing; 2) dopaminergic and other medications causing lower SBP; and 3) suboptimal hydration leading to reduced circulating blood volume.

Note: *Medications include dopaminergic, diuretics, central adrenergic inhibitors, alpha-1 antagonists, nitrates.
Abbreviations: nOH, neurogenic orthostatic hypotension; SBP, systolic blood pressure; s-SBP, standing SBP.

Figure 2 Treatment goals for patients with symptomatic nOH.

Abbreviations: nOH, neurogenic orthostatic hypotension; s-SBP, standing systolic blood pressure.

Figure 3 Management of symptomatic nOH.

Abbreviations: nOH, neurogenic orthostatic hypotension; s-SBP, standing systolic blood pressure.