Influence of serological factors and BMI on the blood pressure/hematocrit association in healthy young men and women

Figures & data

Table 1 Demographic, anthropometric, and serologic characteristics of the young adult population examined in the municipality of the city of Durango, Mexico

Sex	Men =174	Women =442
Age, years	20.4±2.5	19.7±2.2
Weight, kg	75.8± 15.3	60.1±11.8
Height, m	1.74±0.07	1.60±0.06
BMI, kg/m^2	24.8±4.3	23.4±4.1
Mean arterial pressure, mmHg	91.2±7.4	85.0±8.3
Cardiac frequency, beats/minute	67.2±11.5	71.0±11.7
Waist-to-hip ratio	0.94±0.06	0.89±0.06
Body fat, %	22.9±6.5 nr 18%–24%	28.1±8.3 nr 20%–28%
Hematocrit, %	48.2±3.2	43.1±2.8
Cholesterol, mg/dL nr 150–200 mg/dL	163.7±17.4	162.7±16.8*
Glucose, mg/dL nr 70–100 mg/dL	97.4±18.5	95.4±15.1*
Triglycerides, mg/dL nr <150 mg/dL	150.7±98.0	142.9±85.0*

Notes: All demographic and anthropometric parameters, including Hct, are significantly different (P<0.002). Serological parameters (*) are not significantly different.

Abbreviations: BMI; body mass index; nr, normal range; Hct, hematocrit.

Figure 1 MAP plotted as function of Hct for the study population of individuals described in Table 1.

Notes: The association MAP/Hct is positive and significant (P=0.04, r=0.10) for women (n=442) and negative but not significant (r=−0.05) for men (n=174). This association becomes negative but not significant for women when individuals with serological and BMI values exceeding normal values are excluded. The same exclusion applied to men causes the association to become more negative without reaching significance.
Abbreviations: MAP, mean arterial blood pressure; Hct, hematocrit; BMI, body mass index; n, number.

Table 2 Thresholds defining the upper limit of parameters for the normal population

Thresholds	Average and STD of % exceeding threshold
	Men	Women
Cholesterol
200 mg/dL	223.4±22.8; 4.0%	219.3±20.4; 4.1%
Triglycerides
200 mg/dL	300.2±109.5; 21.3%	297.9±108.6; 15.4%
BMI
25 kg/m^2	27.9±3.2; 46.6%	28.5±3.5; 28.7%
Glucose
100 mg/dL	113.7±15.0; 39.1%	110.0±10.0; 36.0%

Abbreviations: STD, standard deviation; BMI, body mass index.

Table 3 Women

	n	m, mmHg/Hct	P	r
All women	442	0.285±0.140	0.04	0.10
All minus chol >200 mg/dL	424	0.214±0.145	ns	0.07
All minus chol, trig >200 mg/dL	363	0.020±0.156	ns	0.00
All minus chol, trig, BMI >25 kg/m^2	266	−0.022±0.178	ns	0.00
All minus chol, trig, BMI, glu >100 mg/dL	166	−0.032±0.213	ns	−0.01

Notes: Statistical characteristics of the association MAP versus Hct as a function of threshold of chol, trig, BMI, and glu.

Abbreviations: MAP, mean arterial blood pressure; m, slope; Hct, hematocrit; chol, cholesterol; trig, triglycerides; BMI, body mass index; glu, glucose; ns, nonsignificant association; n, number.

Table 4 Men

	n	m (slope)	P	r
All men	174	−0.020±0.179	ns	−0.05
All minus chol >200 mg/dL	167	−0.024±0.185	ns	−0.01
All minus chol, trig >200 mg/dL	134	−0.035±0206	ns	−0.02
All minus chol, trig, BMI >25 kg/m^2	77	−0.019±0.260	ns	−0.00
All minus chol, trig, BMI, glu >100 mg/dL	39	−0.193±0.368	ns	−0.09

Notes: Statistical characteristics of the association MAP versus Hct as a function threshold of chol, trig, BMI, and glu.

Abbreviations: m, slope; Hct, hematocrit; chol, cholesterol; trig, triglycerides; BMI, body mass index; glu, glucose; ns, nonsignificant association; n, number.