Transient methemoglobinemia suspected secondary to ingestion of Brassica species in a dog

Figures & data

Table 1 Chemistry and complete blood count results at presentation

Parameter	Results	Unit	Low reference interval	High reference interval
Glu	103	mg/dL	70	143
BUN	17	mg/dL	7	27
Crea	1.2	mg/dL	0.5	1.8
Phos	2.5	mg/dL	2.5	6.8
Ca	10.7	mg/dL	7.9	12
TP	6.4	g/dL	5.2	8.2
Alb	3.4	g/dL	2.2	3.9
Glob	3	g/dL	2.5	4.5
ALT	54	U/L	10	125
ALP	38	U/L	23	212
Tbili	0.3	U/L	0	0.9
Amyl	760	U/L	500	1,500
WBC	13.44	10^9	6	17
RBC	5.42	10^12	5.5	8.5
Hgb	12.8	g/dL	12	18
Hct	36.66	%	37	55
MCV	68	fI	60	77
MCH	23.7	pg	19.5	24.5
MCHC	35	g/dL	31	39
Plt	213	10^9/L	200	500
MPV	8	fI	3.9	11.1
Lymph	2.72	10^9/L	1	4.8
Mono	0.84	10^9/L	0.2	1.5
Neut	9.58	10^9/L	3	12
Eos	0.24	10^9/L	0	0.8
Baso	0.06	10^9/L	0	0.4

Figure 1 A drop of blood from a control canine patient (left) with a drop from the affected patient. The gross appearance of the blood from the affected patient is the chocolate brown coloration consistent with methemoglobinemia.

Table 2 Table recording methemoglobin levels and venous blood gas variables performed during hospitalization

	Initial	6 hrs*	12 hrs*
pH	7.39	7.38	7.36
pCO2	28.5	27.4	42.4
pO2	27.5	48.7	30.8
HCO3	17.5	16.4	23
Hct	35	34	28
MetHb	34.5	3.6	0.1
FiO2	21	21	21

Note: *denotes timing of blood sample following initiation of treatment.

Table 3 Repeat chemistry panel 12 hrs following admission

Parameter	Results	Unit	Low reference interval	High reference interval
Glu	104	mg/dL	70	143
BUN	12	mg/dL	7	27
Crea	1.2	mg/dL	0.5	1.8
Phos	3.6	mg/dL	2.5	6.8
Ca	11.1	mg/dL	7.9	12
TP	7.3	g/dL	5.2	8.2
Alb	2.9	g/dL	2.2	3.9
Glob	4.4	g/dL	2.5	4.5
ALT	73	U/L	10	125
ALP	63	U/L	23	212
Tbili	0.4	mg/dL	0	0.9
Amyl	772	U/L	500	1,500