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Original Research

Prospective Clinical Evaluation of Intra-Articular Injection of Tin-117m (^117mSn) Radiosynoviorthesis Agent for Management of Naturally Occurring Elbow Osteoarthritis in Dogs: A Pilot Study

Karanvir S Aulakh1 School of Veterinary Medicine, Louisiana State University, Baton Rouge, LA, USACorrespondence[email protected]

Mandi J Lopez1 School of Veterinary Medicine, Louisiana State University, Baton Rouge, LA, USA

Caleb Hudson2 Gulf Coast Veterinary Specialists, Houston, TX, USA

Lorrie Gaschen1 School of Veterinary Medicine, Louisiana State University, Baton Rouge, LA, USA

Michelle Fabiani2 Gulf Coast Veterinary Specialists, Houston, TX, USA

Brian Beale2 Gulf Coast Veterinary Specialists, Houston, TX, USA

Frank M Andrews1 School of Veterinary Medicine, Louisiana State University, Baton Rouge, LA, USA

Chin-Chi Liu1 School of Veterinary Medicine, Louisiana State University, Baton Rouge, LA, USA

https://orcid.org/0000-0003-0723-8313

Jimmy Lattimer3 College of Veterinary Medicine, University of Missouri, Columbia, MO, USA

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Figures & data

Table 1 Demographic Characteristics for 21^† Dogs with Naturally Occurring Elbow OA Based on ^117mSn Dose Group

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Table 2 Canine Brief Pain Inventory (CBPI) Scores for 21 Dogs^† with Elbow OA at Pretreatment and at Each Time-Point Post Treatment. Values are Presented as Median (Range)

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Table 3 Evolution of Elbow Extension, Flexion and Range of Motion from Baseline to Month-12 in Treated and Untreated Elbows in 21 Dogs with Elbow OA for All Three ^117mSn Dose Groups. The Means of Three Values for Elbow Extension and Flexion Were Recorded Bilaterally. The Data is Summarized as Mean ± Standard Deviation (SD)

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Table 4 Evolution of PVF and BW-D% from Baseline to Month-12 in Nineteen^† Dogs with Elbow OA for All Three ¹¹⁷Sn Dose Groups. The Data is Summarized as Mean ± Standard Deviation (SD)

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Table 5 Dog Number, ^117mSn Dose Group, and Treatment Outcome in 19 Dogs Undergoing Force-Plate Analysis

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Table 6 Radiographic OA Scores for Treated and Untreated Elbows for Study Dogs with Elbow OA at Pretreatment and at 12-Month Recheck. The 12-Month Radiographs Were Available for 18 Dogs

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Prospective Clinical Evaluation of Intra-Articular Injection of Tin-117m (^117mSn) Radiosynoviorthesis Agent for Management of Naturally Occurring Elbow Osteoarthritis in Dogs: A Pilot Study

Table 1 Demographic Characteristics for 21^† Dogs with Naturally Occurring Elbow OA Based on ^117mSn Dose Group

Table 2 Canine Brief Pain Inventory (CBPI) Scores for 21 Dogs^† with Elbow OA at Pretreatment and at Each Time-Point Post Treatment. Values are Presented as Median (Range)

Table 4 Evolution of PVF and BW-D% from Baseline to Month-12 in Nineteen^† Dogs with Elbow OA for All Three ¹¹⁷Sn Dose Groups. The Data is Summarized as Mean ± Standard Deviation (SD)

Table 5 Dog Number, ^117mSn Dose Group, and Treatment Outcome in 19 Dogs Undergoing Force-Plate Analysis

Table 6 Radiographic OA Scores for Treated and Untreated Elbows for Study Dogs with Elbow OA at Pretreatment and at 12-Month Recheck. The 12-Month Radiographs Were Available for 18 Dogs

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Prospective Clinical Evaluation of Intra-Articular Injection of Tin-117m (117mSn) Radiosynoviorthesis Agent for Management of Naturally Occurring Elbow Osteoarthritis in Dogs: A Pilot Study

Figures & data

Table 1 Demographic Characteristics for 21† Dogs with Naturally Occurring Elbow OA Based on 117mSn Dose Group

Table 2 Canine Brief Pain Inventory (CBPI) Scores for 21 Dogs† with Elbow OA at Pretreatment and at Each Time-Point Post Treatment. Values are Presented as Median (Range)

Table 4 Evolution of PVF and BW-D% from Baseline to Month-12 in Nineteen† Dogs with Elbow OA for All Three 117Sn Dose Groups. The Data is Summarized as Mean ± Standard Deviation (SD)

Table 5 Dog Number, 117mSn Dose Group, and Treatment Outcome in 19 Dogs Undergoing Force-Plate Analysis

Table 6 Radiographic OA Scores for Treated and Untreated Elbows for Study Dogs with Elbow OA at Pretreatment and at 12-Month Recheck. The 12-Month Radiographs Were Available for 18 Dogs

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Prospective Clinical Evaluation of Intra-Articular Injection of Tin-117m (^117mSn) Radiosynoviorthesis Agent for Management of Naturally Occurring Elbow Osteoarthritis in Dogs: A Pilot Study

Table 1 Demographic Characteristics for 21^† Dogs with Naturally Occurring Elbow OA Based on ^117mSn Dose Group

Table 2 Canine Brief Pain Inventory (CBPI) Scores for 21 Dogs^† with Elbow OA at Pretreatment and at Each Time-Point Post Treatment. Values are Presented as Median (Range)

Table 4 Evolution of PVF and BW-D% from Baseline to Month-12 in Nineteen^† Dogs with Elbow OA for All Three ¹¹⁷Sn Dose Groups. The Data is Summarized as Mean ± Standard Deviation (SD)

Table 5 Dog Number, ^117mSn Dose Group, and Treatment Outcome in 19 Dogs Undergoing Force-Plate Analysis