Methicillin-resistant Staphylococcus aureus colonization and infection risks from companion animals: current perspectives

Figures & data

Table 1 Characteristics differentiating between health care and community-associated MRSA (HA-MRSA, CA-MRSA) infections in humans

	HA-MRSA	CA-MRSA
Phenotype	Resistant	Susceptible
Patients	In contact with health care settings	No previous contact with health care settings
Age	Older	Younger
Infections	Septicemia, pneumonia, ventilator-associated pneumonia, surgical site infections	Skin and soft tissue infections, necrotizing pneumonia
SCCmec types	I–III	IV–V
PVL	Negative	Positive
Clones
Europe	ST239	ST80
USA	ST5	ST1, ST8
Australia	ST22, ST239	ST93, ST30
Asia	ST239, ST5	ST59, ST30, ST72

Note: Data from Knox et al,¹⁴ Song et al,¹⁵ Pantosti,¹⁶ and Morris et al.¹⁷

Abbreviations: MRSA, methicillin-resistant Staphylococcus aureus; HA-MRSA, health care-associated MRSA; CA-MRSA, community-associated MRSA; PVL, Panton–Valentine leukocidin.

Table 2 Methicillin-resistant S. aureus (MRSA) most common clones identified in humans and animals according to location

Clonal complex	Sequence type	Hosts	Location	References
CC1	ST1	Humans, pigs, cattle, horses	Europe, South America, Australia	^Citation16,Citation18,Citation67
CC5	ST5 (USA100)	Humans, pigs, cattle, horses, poultry, companion animals	Worldwide	^Citation16,Citation18,Citation21,Citation22,Citation52,Citation63,Citation65,Citation67
CC8	ST8 (USA500), ST239, ST254	Humans, pigs, cattle, horses, companion animals, exotic animals	USA, Canada, Japan, Europe, Australia, People’s Republic of China, South Korea	^Citation16,Citation18,Citation22,Citation52,Citation68^–^Citation70,Citation72
CC9	ST9	Horses, pigs	Europe, Canada, People’s Republic of China, Malaysia, Thailand	^Citation16,Citation18
CC22	ST22, ST36	Humans, companion animals, horses, exotic animals	Europe, People’s Republic of China, Australia	^Citation16,Citation18,Citation21,Citation22,Citation64,Citation65,Citation67,Citation69,Citation72
CC30	ST30, ST36	Humans, companion animals	South America, Europe	^Citation64,Citation66
CC59	ST59	Humans, companion animals	Malaysia, People’s Republic of China	^Citation70,Citation71
CC80	ST80	Humans, companion animals	Europe	^Citation69
CC97	ST97	Humans, pigs, cattle, goats, sheep, rats, ostrich	Europe, South America	^Citation16,Citation18
CC59		Humans, companion animals	People’s Republic of China, Malaysia	^Citation18
CC130	ST130	Humans, cattle	Europe	^Citation16
CC133	ST133	Human, sheep, goats	Europe	^Citation16
CC398	ST398	Pigs, humans, cattle, poultry, horses, rats, companion animals	Europe, People’s Republic of China	^Citation16,Citation21,Citation22,Citation65,Citation67^–^Citation70

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