A simple method for assessing the strength of evidence for association at the level of the whole gene

Figures & data

Table 1 Markers spanning HTRA2 showing individual p values obtained for tests for association with Parkinson’s disease

Marker	Position	P value
		Single marker	Two markers	Three markers
rs6718621	74512208	0.104	0.223	0.343
rs6751601	74536436	0.224	0.084	0.501
rs2240444	74553279	0.061	0.225	0.357
rs2268424	74560023	0.133	0.303	0.596
rs2268420	74566516	0.689	0.564	0.728
rs2268418	74576122	0.166	0.505	0.623
rs7556852	74581170	0.200	0.392	0.691
rs6746854	74593157	0.218	0.326	0.326
rs1063588	74602033	0.149	0.149	0.259
rs1047911	74611433	0.149	0.259	0.136
rs6707475	74622146	0.206	0.109	0.141
rs2301984	74632710	0.155	0.218	0.404
rs2240442	74645428	0.097	0.255	0.260
rs3806607	74647269	0.212	0.152	0.034
rs2241027	74670321	0.041	0.175	0.369
rs6707302	74673077	0.273	0.637	0.617
rs7562200	74688601	0.841	0.326	0.515
rs11126435	74701355	0.126	0.465
rs10170219	74715172	1.000