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Review

Testosterone depot injection in male hypogonadism: a critical appraisal

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Pages 577-590 | Published online: 19 Oct 2022

Figures & data

Figure 1 Trough levels of testosterone after repeated injections of testosterone enanthate and testosterone undecanoate in 40 hypogonadal men (mean age 41, range: 18–74 years).

Figure 1 Trough levels of testosterone after repeated injections of testosterone enanthate and testosterone undecanoate in 40 hypogonadal men (mean age 41, range: 18–74 years).

Figure 2 Sexual parameters in 40 hypogonadal men (mean age 41, range: 18–74 years) under treatment with testosterone enanthate or testosterone undecanoate.

Figure 2 Sexual parameters in 40 hypogonadal men (mean age 41, range: 18–74 years) under treatment with testosterone enanthate or testosterone undecanoate.

Figure 3 Effect of testosterone undecanoate (intervals of 12-weeks) on prostate-specific antigen (PSA) in 40 hypogonadal men (mean age 41, range: 18–74 years).

Figure 3 Effect of testosterone undecanoate (intervals of 12-weeks) on prostate-specific antigen (PSA) in 40 hypogonadal men (mean age 41, range: 18–74 years).

Figure 4 Disappearance of venous leakage evidenced by cavernosography in a hypogonadal man with erectile dysfunction at baseline (left) and after 3 months’ administration of testosterone undecanoate (right).

Figure 4 Disappearance of venous leakage evidenced by cavernosography in a hypogonadal man with erectile dysfunction at baseline (left) and after 3 months’ administration of testosterone undecanoate (right).

Figure 5 Another subject showing absence of venous leakage evidenced by cavernosography in a hypogonadal man with erectile dysfunction at baseline (left) and after 4.5 months’ administration of testosterone undecanoate (right) with better penile composition and opacification.

Figure 5 Another subject showing absence of venous leakage evidenced by cavernosography in a hypogonadal man with erectile dysfunction at baseline (left) and after 4.5 months’ administration of testosterone undecanoate (right) with better penile composition and opacification.

Figure 6 Improvement in scores on the international index of erectile function (IIEF) in 71 of 122 patients receiving treatment with long-acting testosterone undecanoate.

Figure 6 Improvement in scores on the international index of erectile function (IIEF) in 71 of 122 patients receiving treatment with long-acting testosterone undecanoate.