Reappraisal of the role of dolasetron in prevention and treatment of nausea and vomiting associated with surgery or chemotherapy

Figures & data

Figure 1 Schematic representation of the mechanisms of emesis associated with chemotherapy-induced and postoperative nausea and vomiting.

Figure 2 Metabolic pathways of dolasetron.

Abbreviations: CYP2D6, cytochrome P450 2D6 isoform; CYP3A, cytochrome P450 3A isoform; Mx, metabolism.