Mitochondrial function in diaphragm of emphysematous hamsters after treatment with nandrolone

Figures & data

Table 1 Bodyweights and lung volumes (mean ± SEM)

	NH CON (n = 9)	EH CON (n = 12)	NH ND (n = 10)	EH ND (n = 14)
Initial bodyweight (g)	141 ± 5	127 ± 4a	146 ± 3	131 ± 3a
Final bodyweight (g)	144 ± 6	129 ± 4	140 ± 3b	121 ± 3b
Lung volume (mL)	10.9 ± 0.5	15.7 ± 1.8c	12.2 ± 0.8	18.3 ± 2.6c,d

a p < 0.05 EH vs NH.

b p < 0.05 before vs after treatment.

c p < 0.001 EH vs NH.

d p < 0.01 EH ND vs EH CON.

Abbreviations: CON, control group; EH, emphysematous hamster; NH, normal hamster; ND, nandrolone group.

Figure 1 Serum testosterone concentration.

^a p < 0.05 vs NH CON group.

^b p < 0.05 vs EH CON group.

Abbreviations Figures 1–5: NH, normal hamster; EH, emphysematous hamster; CON, control group; ND, nandrolone group.

Figure 2 Activity of citrate synthase (CS) in the diaphragm.

Figure 3 Activity of succinate: cytochrome c oxidoreductase (SCC) in the diaphragm.

^a p < 0.05 vs NH ND group.

Figure 4 Activity of complex III (C-III) in the diaphragm.

Figure 5 Activity of complex IV (C-IV) in the diaphragm.