Figures & data
Figure 1 Single data and mean value of total cell numbers in (A) BAL fluid and (B) in separated lung tissue. There were three animals in each experiment with the following exceptions: statin treatment 1 mg IP (two experiments each, n = 6) and statin treatment 1 mg IT (one experiment, n = 1 and one experiment, n = 9). The reduction in total cell numbers in BAL fluid after simvastatin 10 mg treatment was significant compared with the control group (P < 0.05). No differences were found between cell numbers isolated from lung tissue.
Figure 2 Single data and mean values of (A) eosinophils and (B) neutrophils in BAL fluid. A significant reduction in eosinophil numbers in BAL fluid was found compared with the control groups in the first experiment after simvastatin 10 mg IP and in the first experiment after simvastatin 0.1 mg IT (P < 0.05). Neutrophils were reduced significantly after simvastatin 10 mg.
Figure 3 Single data and mean values for (A) CD4 T cells and (B) dendritic cells in BAL fluid. CD4 T cells were significantly reduced in all simvastatin treatment groups except for the two simvastatin 0.1 mg IP groups (P < 0.05). No differences were found between dendritic cell numbers.
