New approaches in the management of insomnia: weighing the advantages of prolonged-release melatonin and synthetic melatoninergic agonists

Figures & data

Figure 1 Chemical structures and main metabolic routes of melatonin and synthetic melatoninergic hypnotics. Flashes = sites of metabolic reactions.

Abbreviations: AFMK, N¹-acetyl-N²-formyl-5-methoxykynuramine; Me, methyl; mel, melatonin; 5-MT, 5-methoxytryptamine; NAS, N-acetylserotonin. For other details see current text.