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Original Research

A single nucleotide polymorphism analysis of the LAMA1 gene in Japanese patients with high myopia

, , , , , , , , , , & show all
Pages 289-295 | Published online: 25 Nov 2022

Figures & data

Figure 1 13 SNPs analyzed in the LAMA1 gene. Vertical arrows show the 13 SNPs analyzed in this study with the #rs numbers. Left of the figure is 5′ UTR. Black boxes show the translated regions (exons) of this gene with the exon numbers below them.

Figure 1 13 SNPs analyzed in the LAMA1 gene. Vertical arrows show the 13 SNPs analyzed in this study with the #rs numbers. Left of the figure is 5′ UTR. Black boxes show the translated regions (exons) of this gene with the exon numbers below them.

Table 1 Allele frequencies for the 13 SNPs in the LAMA1 gene among the Japanese patients with high myopia

Table 2 Genotype frequencies for the 13 SNPs in the LAMA1 gene among the Japanese patients with high myopia

Figure 2 LD patterns of the LAMA1 locus. Pairwise LD between SNPs within LAMA1 locus are evaluated by D′ Structures of low to high LD in the LAMA1 locus are shown in colored region. The case is above and the control is below the diagonal line.

Figure 2 LD patterns of the LAMA1 locus. Pairwise LD between SNPs within LAMA1 locus are evaluated by D′ Structures of low to high LD in the LAMA1 locus are shown in colored region. The case is above and the control is below the diagonal line.

Table 3 Frequency analysis of the estimated haplotype for the SNPs within the LAMA1 gene in Japanese myopia patients and control subjects