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Original Research

Diclofenac prevents temporal increase of intraocular pressure after uneventful cataract surgery with longer operation time

, , , &
Pages 95-101 | Published online: 25 Nov 2022

Figures & data

Figure 1 Clinical course in IOP after the cataract surgery in eyes with postoperative topical administration of betamethasone (closed circle) and that of diclofenac (open circle). The vertical bar indicates standard deviation of the mean. After 4 postoperative weeks, IOP in the betamethasone-treated eye showed a significant increase with compared to that in diclofenac-treated eye. The asterisk (*) indicates statistical significance (p < 0.05).

Figure 1 Clinical course in IOP after the cataract surgery in eyes with postoperative topical administration of betamethasone (closed circle) and that of diclofenac (open circle). The vertical bar indicates standard deviation of the mean. After 4 postoperative weeks, IOP in the betamethasone-treated eye showed a significant increase with compared to that in diclofenac-treated eye. The asterisk (*) indicates statistical significance (p < 0.05).

Figure 2 Relationship between the ΔIOP and total surgery time in uneventful cataract surgery in postoperative betamethasone-treated eyes (A) and diclofenac-treated eyes (B) Strong correlation was observed in betamethasone-treated eye (r = 0.499, p = 0.002), in contrast little correlation was seen in diclofenac-treated eyes (r = 0.044, p = 0.763).

Figure 2 Relationship between the ΔIOP and total surgery time in uneventful cataract surgery in postoperative betamethasone-treated eyes (A) and diclofenac-treated eyes (B) Strong correlation was observed in betamethasone-treated eye (r = 0.499, p = 0.002), in contrast little correlation was seen in diclofenac-treated eyes (r = 0.044, p = 0.763).

Figure 3 Relationship between the ΔIOP and EPT in uneventful cataract surgery in postoperative betamethasone-treated eyes (A) and diclofenac-treated eyes (B) Strong correlation was observed in betamethasone-treated eye (r = 0.535, p < 0.001), in contrast little correlation was seen in diclofenac-treated eyes (r = −0.080, p = 0.584).

Figure 3 Relationship between the ΔIOP and EPT in uneventful cataract surgery in postoperative betamethasone-treated eyes (A) and diclofenac-treated eyes (B) Strong correlation was observed in betamethasone-treated eye (r = 0.535, p < 0.001), in contrast little correlation was seen in diclofenac-treated eyes (r = −0.080, p = 0.584).

Table 1 Multiple regression analysis for alteration of ΔIOP in betamethasone-treated eyes

ANOVA table from multiple regression equation of y = improvement of VA

Table 2 Multiple regression analysis for alteration of ΔIOP in diclofenac-treated eyes

ANOVA table from multiple regression equation of y = improvement of VA