Efficacy of amniotic membrane-assisted bleb revision for elevated intraocular pressure after filtering surgery

Figures & data

Table 1 Patient demographics

	Amniotic membrane
	−	+
	(n = 24)	(n = 12)	P value
Age (years)
Mean ± SD	61.7 ± 13.1	61.4 ± 16.6	0.675*
Range	36–84	38–83
Follow-up period (months)
Mean ± SD	9.6 ± 4.5	9.6 ± 4.9	0.931*
Range	6–20	6–16
Preoperative IOP (mmHg)
Mean ± SD	21.4 ± 6.5	21.8 ± 4.6	0.469*
Range	15–48	16–30
Prior surgeries
Cataract	15	9	0.708†
Vitrectomy	4	6	0.053†
Filtering 1	15	6	0.499†
Surgery <2	9	6
Number of eye drops	1.4 ± 0.9	1.5 ± 1.0	0.918*

* Mann-Whitney’s U test;

† Fisher’s exact probability test.

Abbreviations: SD, standard deviation; IOP, intraocular pressure.

Table 2 Type of glaucoma

	Amniotic membrane
	−	+
	(n = 24)	(n = 12)	P value
Primary open angle glaucoma	11	7	0.725
Exfoliation syndrome	2	0	0.543
Glaucoma secondary to uveitis	4	1	0.635
Neovascular glaucoma	5	4	0.416
Others	2	0	0.543

Figure 1 Kaplan-Meier survival curves of the amnion and nonamnion transplant groups. A plot of the cumulative probabilities against time that the intraocular pressure was 30% lower than at baseline.

Table 3 Postoperative complications

	Amniotic membrane
	−	+
	(n = 24)	(n = 12)	P value
Shallow anterior chamber	1	0	➢ 0.999
Choroidal detachment	1	0	➢ 0.999
Hyphema	2	1	➢ 0.999
Wound leakage	1	3	0.098