A patient preference comparison of Azarga^™ (brinzolamide/timolol fixed combination) vs Cosopt^® (dorzolamide/timolol fixed combination) in patients with open-angle glaucoma or ocular hypertension

Figures & data

Table 1 Demographics of participating patients (n = 129)

Mean age (yr)	66.2 ± 11.4
Gender, n (%)
Female	65 (50.4)
Male	64 (49.6)
Race, n (%)
Caucasian	94 (72.9)
Black or African-American	23 (17.8)
Hispanic	10 (7.8)
Other	2 (1.6)
Diagnosis, n (%)
Open-angle glaucoma	100 (77.5)
Ocular hypertension	29 (22.5)

Figure 1 Percentage patient preference among those stating a preference (n = 106; p < 0.0001).

Figure 2 Ocular discomfort scores.

*p < 0.0001.

ITT = intent-to-treat

Table 2 Summary of adverse events, n (%)

	Brinzolamide/timolol	Dorzolamide/timolol	p value
Ocular irritation	7 (5.5)	22 (17.3)	0.0029
Ocular pain	1 (0.8)	10 (7.9)	0.0053
Blurred vision	19 (14.8)	1 (0.8)	< 0.0001
Other
Foreign body sensation	1 (0.8)	0 (0)	–
Increased tearing	0 (0)	1 (0.8)	–
Taste perversion	1 (0.8)	0 (0)	–