A randomized clinical evaluation of the safety of Systane^® Lubricant Eye Drops for the relief of dry eye symptoms following LASIK refractive surgery

Figures & data

Figure 1 Corneal regions and staining grades.

Figure 2 Conjunctival regions and staining grades.

Table 1 Comparison of tear film break-up time (TFBUT) between Systane^®-treated eyes and placebo-treated eyes

Variable	# of eyes	Systane^®		Placebo		p valuea
		Mean (SD)	Range	Mean (SD)	Range
Visit 1 (screening)	30	7.42 (3.68)	2.67–14.00	7.80 (3.26)	3.00–12.67	0.2757
Visit 2 (Day 0)	30	6.94 (3.66)	2.33–21.00	7.63 (3.58)	2.33–19.33	0.0703
Visit 3 (Day 1)	30	5.17 (2.04)	1.33–9.00	5.57 (2.67)	1.00–12.33	0.3535
Visit 4 (Day 14 ± 3)	30	6.40 (3.10)	2.33–14.00	5.17 (2.37)	2.00–11.67	0.0281
Visit 5 (Day 30 ± 7)	30	6.33 (3.18)	2.00–15.00	6.28 (2.81)	2.00–13.33	0.8662

a p values of the paired t-test for comparisons between the two treatments using contralateral eyes as controls.