Preliminary results following the use of a fixed combination of timolol–brimonidine in patients with ocular hypertension and primary open-angle glaucoma

Figures & data

Table 1 Intraocular pressure-lowering drugs used before initiation of the fixed combination timolol–brimonidine and their percentage

Medication	No of patients	(%)
No medication	6	12%
Brimonidine	3	6%
Timolol	5	10%
Latanoprost	7	14%
Travoprost	2	4%
Bimatoprost	2	4%
Dorzolamide	2	4%
Timolol/Dorzolamide	14	28%
Latanoprost/Timolol	9	18%
Total	50

Figure 1 Mean intraocular pressure (IOP) change.

Table 2 Number of eyes that presented the specific sign at the 1st and/or 2nd month, with no prior involvement

Ophthalmic signs	1st month	2nd month
Conjunctival secretions	3	3
Conjunctiva	4	4
Corneal epithelial disease	1	0
Total number of patients	4*	5**

Notes: *One patient had three signs and one patient had two signs;

** Two patients had two signs.

Table 3 Eyes that presented with symptoms at 1st and 2nd month, but were not present at the baseline examination

Months	Stinging	Burning	Pain
1st month	2	0	1
2nd month	2	2	0