Role of prostaglandins and specific place in therapy of bimatoprost in the treatment of elevated intraocular pressure and ocular hypertension: A closer look at the agonist properties of bimatoprost and the prostamides

Figures & data

Figure 1 A) Chemical structure of bimatoprost B) Pathway for the production of prostaglandin ethanolamides (prostamides) via COX-2 mediated conversion of the major endocannabinoid, anandamide. Only Prostamide F_2α is shown for brevity. Comparison is made alongside conventional prostaglandin production via COX enzymes, showing PGF_2α as an example.

Abbreviation: FAAH, fatty acid amide hydrolase.