Intracameral vancomycin following cataract surgery: An eleven-year study

Figures & data

Figure 1 Distribution of number cataract surgeries performed over the study period.

Figure 2 Distribution of cases of endophthalmitis over the study period showing cumulative incidence.

Table 1 Incidence of endophthalmitis before and after introduction of intracameral vancomycin prophylaxis

	Cataract surgeries	Endophthalmitis cases	Incidence
Period A 1998–2000 (Preintracameral vancomycin)	3904	13	0.3 per 100
Period B 2000–2008 (Postintracameral vancomycin)	12702	1	0.008 per 100

Table 2 Characteristics of cases of presumed endophthalmitis after cataract surgery over the 11-year study period

Case	Year	Age	Section	Intraoperative complication	Suture	Onset of symptoms	Intraocular antibiotic (Intravitreal or intracameral)	Organism on gram stain or culture	Visual acuity at last visit
Period A
Case 1	1998	85	Clear corneal	Nil	Nil	2 days	Nil	Negative	HM
Case 2	1998	80	Scleral tunnel	Nil	10.0 nylon	9 days	Vancomycin, Ceftazidime	Negative	6/12
Case 3	1998	76	Clear corneal	Nil	Nil	2 days	Vancomycin, Ceftazidime	Gram-positive cocci	6/12
Case 4	1998	85	Scleral tunnel	Nil	Nil	1 day	Gentamicin, Vancomycin	Streptococcus pneumoniae	No PL
Case 5	1999	91	Scleral tunnel	Nil	Nil	10 days	Vancomycin, Ceftazidime	Negative	6/60
Case 6	1999	65	Clear corneal	Nil	Nil	2 days	Cefuroxime, Vancomycin	Psuedomonas aeruginosa	6/9
Case 7	1999	52	Clear corneal	Nil	Nil	2 days	Teicoplanin, Ciprofloxacin	Nil	6/12
Case 8	2000	80	Scleral tunnel	Nil	Nil	1 day	Vancomycin, Ceftazidime	Streptococcus pneumoniae	No PL
Case 9	2000	69	Clear corneal	Nil	10.0 nylon	5 days	Teicoplanin, Ciprofloxacin	Streptococcus pneumonia	6/18
Case 10	2000	75	Scleral tunnel	Nil	Nil	6 days	Cefuroxime, Vancomycin	Negative	6/36
Case 11	2000	60	Scleral tunnel	Nil	Nil	3 days	Vancomycin, Ceftazidime	Negative	6/9
Case 12	2000	78	Scleral tunnel	Nil	Nil	14 days	Vancomycin, Ceftazidime	Negative	6/12
Case 13	2000	93	Scleral tunnel	Nil	Nil	2 days	Vancomycin, Ceftazidime	Negative	No PL
Period B
Case 14	2008	73	Clear corneal	Nil	Nil	2 days	Vancomycin, Ceftazidime	Negative	6/6