Hepatic progenitors for liver disease: current position

Figures & data

Figure 1 Cells contributing to liver regeneration.

Notes: Different cellular types regulate liver regeneration on several levels. Contribution of mature hepatocytes to regeneration of hepatic parenchymal cells is shown in black. Liver precursor cells with bipotential differentiation capacity are shown in red. Proposed pathways of liver regeneration, which require further clarification, are shown in grey.
Abbreviations: HSC, hepatic stem cells; MSC, mesenchymal stem cells.

Figure 2 Markers of oval cells.

Notes: intracellular and surface markers of oval cells in rats and mice differ from liver precursor cells (LPCs) in humans. The most compelling markers that are potentially useful for isolation of oval cells in different species, are shown.