Combating HIV resistance – focus on darunavir

Figures & data

Table 1 Resistance mutations associated with darunavir and tipranavir

Protease codons	10		20	30		40			50	60	70			80	90
Darunavir	V			V L					I I I		G	L	I		L
	II			3233					475054		73	76	84		89
	I			I F					V V M		S	V	V		V
									L
Tirpranavir	L	I	K	L E	M	K	M	I	I	Q	H	T	V	N I	L
	10	13	20	3335	36	43	46	47	54	58	69	74	82	8384	90
	V	V	M	F G	I	T	L	V	A	E	K	P	L	D V	M
			R						M				T
									V