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Review

Brimonidine in the treatment of glaucoma and ocular hypertension

Pages 337-346 | Published online: 24 Dec 2022

Figures & data

Figure 1 Equivalent IOP-lowering efficacy of brimonidine-Purite 0.1% and brimonidine 0.2%. In a 1-year clinical comparison study of the 2 formulations, the 95% CI of the difference in mean IOP between treatment groups (brimonidine-Purite 0.1% minus brimonidine 0.2%) was consistently within the range of −1.5 mmHg to 1.5 mmHg, demonstrating equivalent efficacy of the study formulations.

Abbreviations: CI, confidence interval; IOP, intraocular pressure.
Figure 1 Equivalent IOP-lowering efficacy of brimonidine-Purite 0.1% and brimonidine 0.2%. In a 1-year clinical comparison study of the 2 formulations, the 95% CI of the difference in mean IOP between treatment groups (brimonidine-Purite 0.1% minus brimonidine 0.2%) was consistently within the range of −1.5 mmHg to 1.5 mmHg, demonstrating equivalent efficacy of the study formulations.

Figure 2 Mean change from baseline IOP. Both brimonidine-Purite 0.1% and brimonidine 0.2% provided significant IOP reductions that were sustained throughout 1 year of therapy. The mean IOP reduction was equivalent with the 2 formulations throughout follow-up.

Abbreviations: IOP, intraocular pressure.
Figure 2 Mean change from baseline IOP. Both brimonidine-Purite 0.1% and brimonidine 0.2% provided significant IOP reductions that were sustained throughout 1 year of therapy. The mean IOP reduction was equivalent with the 2 formulations throughout follow-up.