Evaluation of cardiotoxicity five years after 2D planned, non-simulated, radiation therapy for left breast cancer

Figures & data

Table 1 Clinical manifestations, ECG changes, and echocardiographic parameters 6 months before and 5 years after radiotherapy for left breast cancer

	Before RT (n = 62)	Six months after RT (n = 62)	Five years after RT (n = 62)
Clinical symptoms
Angina	0	0	0
Hypertension	24	25	31 (p < 0.05)
ECG changes
QRS and/or ST changes	0	1	3
Other ECG changes	0	1	2
Echocardiographic findings
Pericardial fluid	0	1	0
EDV (mL)	111.5 ± 17.9	112.5 ± 13.7	117.5 ± 17.1
ESV (mL)	43.8 ± 7.5	43.9 ± 8.4	45.8 ± 9.5
EF (%)	65.7 ± 7.9	65.3 ± 6.8	63.4 ± 7.1
LVIDd (cm)	5.1 ± 0.4	5.2 ± 0.8	5.4 ± 0.5
LVIDs (cm)	3.7 ± 0.7	3.8 ± 0.9	3.9 ± 0.6
LVPwd (cm)	0.71 ± 0.2	0.72 ± 0.2	0.74 ± 0.1
IVSd (cm)	0.75 ± 0.3	0.76 ± 0.1	0.79 ± 0.1
IVSs (cm)	1.01 ± 0.2	1.02 ± 0.3	1.04 ± 0.2

Abbreviations: EDV, end diastolic volume; ESV, end systolic volume; EF, ejection fraction; LVIDd, left ventricular internal dimension in diastole; LVIDs, left ventricular internal dimension in systole; IVSd, interventricular septum in diastole; IVSs, interventricular septum in systole.